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Impact of Ethnic Origin and Quinidine Administration on Codeine's Disposition and Paharmacodynamic E

Impact of Ethnic Origin and Quinidine Administration on Codeine's Disposition and Paharmacodynamic E

  1. Jatelka
    Originally published in JPET

    Looks at the effect of ethnic origin on the metabolism of codeine (mediated by the cytochrome system). Chinese subjects produce less morphine from codeine and are less sensitive to morphine.