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Intranasal Drug Delivery: How, Why and What for?

Intranasal Drug Delivery: How, Why and What for?

  1. methylman251
    Intranasal Drug Delivery: How, Why and What for?
    Pires A, Fortuna A et al. 1,2 J Pharm Pharmaceut Sci 12(3) 288 - 311, 2009
    Abstract:
    Over the recent decades the interest in intranasal delivery as a non-invasive route for drugs is increased.
    Since the nasal mucosa offers numerous benefits as a target tissue for drug delivery, a wide variety of
    therapeutic compounds may be administered intranasally for topic, systemic and central nervous system
    action. We have, herein, outlined the relevant aspects of nasal anatomy, physiology and histology, and the
    biological, physicochemical and pharmaceutical factors that must be considered during the process of
    discovery and development of nasal drugs as well as in their incorporation into appropriate nasal
    pharmaceutical formulations.