Methamphetamine Reduces Human Influenza A Virus Replication

Evidence of antiviral properties in methamphetamine with regard to human influenza virus.

  1. Allthatglitters
    Study Author(s):
    Yun-Hsiang Chen, Kuang-Lun Wu, and Chia-Hsiang Chen
    Journal Name:
    PLoS One. 2012; 7(11): e48335.
    Publication Date:
    November 6, 2012
    PMID:
    3491060
    From the abstract:
    “Herein, we investigated the effects of meth on influenza A virus replication in human lung epithelial A549 cells. The cells were exposed to meth and infected with human influenza A/WSN/33 (H1N1) virus. The viral progenies were titrated by plaque assays, and the expression of viral proteins and cellular proteins involved in interferon responses was examined by Western blotting and immunofluorescence staining. We report the first evidence that meth significantly reduces, rather than increases, virus propagation and the susceptibility to influenza infection in the human lung epithelial cell line, consistent with a decrease in viral protein synthesis.”

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  1. the elusive eye
    the elusive eye
    5/5,
    Version: 1
    unexpected to say the least...good to know the positive effects aren't purely subjective! great find.
  2. Alfa
    Alfa
    5/5,
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    A fascinating study about a positive health effect of methamphetamine.