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Methylphenidate for Interferon Induced depression (2006)

Methylphenidate for Interferon Induced depression (2006)

  1. Jatelka
    Journal of Psychopharmacology 2006 Sep;20(5):687-9

    Camacho A (http://www.ncbi.nlm.nih.gov/sites/e...l.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus), Ng B (http://www.ncbi.nlm.nih.gov/sites/e...l.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus).

    Interferon-Alpha (IFN) has been effective in the treatment of chronic viral infections and cancer albeit the added risk of severe depression. The literature has reported effectiveness in the use of antidepressants for interferon-induced depression. We report a case of severe protracted depression induced by IFN in a patient diagnosed with melanoma who responded rapidly to a course of methylphenidate using the Hamilton Depressive Rating Scale. Methylphenidate appeared to be effective in the treatment of neurovegetative symptoms of major depression induced by IFN. This report provides further clinical evidence that the neurovegetative symptoms of depression might respond better to a norepinephrine uptake inhibitor or psycho-stimulants

    A fascinating case report on Ritalin for a (very specific) form of depression.

Recent Reviews

  1. Laudaphun
    Version: 2006-08-07
    Indeed, SWIM's marmoset was able to effectively alleviate depression, among other unpleasant effects caused by pegylated interferon alfa 2a at dosage 180mcg/week. Dosages need to be adjusted as needed as the marmoset reported that 1 of 15 variables caused the dosage necessary to be 1/2 what she normally took. LOTS of interactions and strange things, so tread lightly, in particular with herbs and vitamins.... but that's just SWIM's marmoset.