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Naltrexone in pain management

Naltrexone in pain management

  1. 0utrider
    This paper provides an overview of naloxone and naltrexonepharmacology, and briefly examines some of the theoretical foundations of opioid antagonists for pain management. Available evidence from the literature describing opioid-antagonist therapy in adult humans, as portrayed in case examples or clinical trials, is reviewed and summarized. It must be understood, however, that opioid antagonists are not yet FDA-approved as adjuvant analgesics or for other pain management purposes, so their uses described in this report are off-label. Further investigations to assess the safety and efficacy of these applications would be appropriate.