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One hundred years of barbiturates and their saint (2004)

One hundred years of barbiturates and their saint (2004)

  1. Jatelka
    Journal of the Royal Society of Medicine 2004 Dec;97(12):594-8.

    Cozanitis, Dimitri A

    Soporifics were limited to alcohol and opium until 1869, when chloral hydrate was first used as a sedative and hypnotic. Urethane, bromides, chlorbutanol, sulphones, hederal and chloralose then followed. In 1863, Johan Adolf Baeyer discovered malonylurea, a substance that would become the parent compound of the barbiturates. The date of this discovery is believed to have been 4 December, and on that same day Baeyer visited a tavern frequented by artillery officers. 4 December is the feast day of Saint Barbara, patron saint of artillery-men as well as tunnellers and firemen; thus he designated his malonylurea barbituric acid