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Reduction in incidence of severe paracetamol poisoning (2000)

Reduction in incidence of severe paracetamol poisoning (2000)

  1. Calliope
    The Lancet, Volume 355, Issue 9220, 10 June 2000, Pages 2047-2048

    Martin I Prince, Simon H L Thomas, Oliver F W James, Mark Hudson

    Abstract
    We report substantial reductions in the frequency of severe paracetamol hepatotoxicity locally and nationally after legislative limitations on its sale. These reductions were not explained by changes in referral patterns or use of N-acetylcysteine.

    This file also contains a second research letter from the same issue of the Lancet:

    Change in occurrence of paracetamol overdose in UK after introduction of blister packs (2000)
    The Lancet, Volume 355, Issue 9220, 10 June 2000, Pages 2048-2049
    JL Turvill, AK Burroughs, KP Moore
    Abstract
    Since the introduction of new regulations that limit the availability of paracetamol in the UK, there has been a substantial decrease in the occurrence and severity of cases of paracetamol overdose.