Latest Reviews

  1. aemetha
    For {Study} in Opiate Addiction
    aemetha
    4/5,
    Version: 1
    I would suggest the study on its own is not very useful. There are a lot of uncontrolled variables in the data.

    Probably most importantly the data does not adequately capture whether pain is effectively treated. There's quite a bit of data that suggests that pain on its own isn't really predictive of suicide, and instead it's more the case that someone feeling like nothing can be done about the pain that is predictive of suicide. This is consistent with other research into suicide - depression for example is a weak predictor of suicide, but depression and hopelessness is a strong predictor of suicide. Importantly, there is no measure of hopelessness used in the study, probably because the data wasn't captured in the sample they used, but it's a very important omission.

    Another issue, which they mention in the discussion, is there is no indication of whether suicidality predates the opioid use/misuse. Again, this is a very important omission because there is a complex relationship between drug use and mental health which is bi-directional. Without controlling for the possibility that someone is taking opioids because they are suicidal, rather than someone being suicidal because they take opioids, no real conclusions can be drawn as to the causality.

    Overall, it's the type of study that is useful insofar as confirming that there is a problem with opioid misuse and suicidality and highlighting what future research needs to investigate to draw firmer conclusions.
  2. Lat3ris
    For {Study} in Buprenorphine
    Lat3ris
    4/5,
    Version: 1
    Relevant & insightful info. regarding a current issue w/ buprenorphine
  3. Lat3ris
    Lat3ris
    4/5,
    Version: 1
    Good insight into the nature of this behavior
  4. Lat3ris
    For {Study} in Kratom
    Lat3ris
    4/5,
    Version: 2014-04-15
    Excellent informative article regarding this popular substance