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Systematic assessment of gamma hydroxybutyrate (GHB) effects during and after acute intoxication. (2

Systematic assessment of gamma hydroxybutyrate (GHB) effects during and after acute intoxication. (2

  1. ThirdEyeFloond
    Am J Addict. 2008 Jul-Aug;17(4):312-8.

    Kim SY, Barker JC, Anderson IB, Dyer JE, Earnest G, Blanc PD.

    We adapted and tested a previously published questionnaire battery eliciting sensory and cognitive symptoms during (acute) and immediately after (post-acute) GHB intoxication. Studying 125 GHB users, we assessed the instrument's internal consistency using Cronbach's alpha (CA) and responsiveness to change comparing acute and post-acute symptoms. The final 14-item battery demonstrated good internal consistency (CA >or= 0.85, both acute and post-acute). The median symptom score (possible range 0-64) was 30 (acute) and 6 (post-acute; difference p < 0.001). This modified substance-specific symptom battery, which is easily administered, demonstrated excellent performance characteristics. It can be used to study GHB and, potentially, related drugs of abuse.
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