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THE ACTION OF OXALYL CHLORIDE ON INDOLES: A NEW APPROACH TO TRYPTAMINES

THE ACTION OF OXALYL CHLORIDE ON INDOLES: A NEW APPROACH TO TRYPTAMINES

  1. trptamene
    A classic paper that employs the use of indoles, oxalyl chloride, LAH, and substituted amines to give tryptamines. This is the Speeter and Anthony method of tryptamine synthesis.


    From the paper:

    To obtain bufotenine and its relatives in quantity
    for study of their central nervous system effects, a
    new tryptamine synthesis has been developed which
    appears to be of wide scope and general application. (1954)