Many countries have legalised or decriminalised cannabis use, leading to concerns that this might result in an increase in cannabis use and associated harm,even if the latter only affects a minority of the population. Crosssectional and prospective epidemiological studies as well as biological evidence6 support a causal link between cannabis use and psychotic disorder. Metaanalysis shows a dose–response association with the highest odds of psychotic disorder in those with the heaviest cannabis use.7 Nevertheless, it is not clear whether, at a population level, patterns of cannabis use influence rates of psychotic disorder.
- Study Author(s):
- Marta Di Forti, Diego Quattrone, Tom P Freeman, Giada Tripoli, Charlotte Gayer-Anderson, Harriet Quigley, Victoria Rodriguez, Hannah E Jongsma, Laura Ferraro, Caterina La Cascia, Daniele La Barbera, Ilaria Tarricone, Domenico Berardi, Andrei Szöke, Celso Arango, Andrea Tortelli, Eva Velthorst, Miguel Bernardo, Cristina Marta Del-Ben, Paulo Rossi Menezes, Jean-Paul Selten, Peter B Jones, James B Kirkbride, Bart PF Rutten, Lieuwe de Haan, Pak C Sham, Jim van Os, Cathryn M Lewis, Michael Lynskey, Craig Morgan, Robin M Murray, and the EU-GEI WP2 Grou
- Journal Name:
- Publication Date:
- march 19, 2019