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The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan:

The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan:

  1. Mindless
    This study focuses on dextromethorphan but has wider implications concerning the potential of grapefruit and seville orange juice as (pharmacokinetic) potentiators of opioids and other CYP3A substrates.