1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP

The effect of intravenous cimetidine on the absorption of orally administered diazepam and lorazepam

The effect of intravenous cimetidine on the absorption of orally administered diazepam and lorazepam

  1. Jatelka
    British Journal of Pharmacology 1982 Aug;14(2):207-11

    McGowan WA, Dundee JW

    1 The effect of intravenous cimetidine 200 mg or 400 mg on the absorption of lorazepam 2.5 mg tablet and diazepam 10 mg tablet and capsule was studied.
    2 Considerable individual variation in plasma concentrations was found with all preparations.
    3 Cimetidine increased the absorption of diazepam and lorazepam.
    4 Capsule preparations of diazepam generally produced higher drug plasma concentrations than the tablets.