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Toxicity of Kava Kava

Toxicity of Kava Kava

  1. Jasim
    Kava is a traditional beverage of various Pacific Basin countries. Kava has been introduced
    into the mainstream U.S. market principally as an anti-anxiety preparation.
    The effects of the long-term consumption of kava have not been documented adequately.
    Preliminary studies suggest possible serious organ system effects. The potential carcinogenicity
    of kava and its principal constituents are unknown. As such, kava extract was
    nominated for the chronic tumorigenicity bioassay conducted by the National Toxicology
    Program (NTP). At present toxicological evaluation of kava extract is being conducted
    by the NTP. The present review focuses on the recent findings on kava toxicity and the
    mechanisms by which kava induces hepatotoxicity.