Zinc involvement in opioid addiction and analgesia – should zinc supplementation be recommended for

Effects of zinc on opioid tolerance and addiction

  1. aemetha
    Study Author(s):
    D. Ciubotariu, C. M. Ghiciuc, C. E. Lupușoru
    Journal Name:
    Substance Abuse Treatment, Prevention, and Policy
    Publication Date:
    2015
    PMID:
    4523930
    Zinc chelators were shown to facilitate some opioid-withdrawal signs in animals. Zinc deficiency, which affects more than 15 % the world’s population, is also common among opioid consumers and opioid-treated animals exhibit misbalances of zinc distribution.