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2-DPMP

Discussion in 'Drug Articles' started by NeuroChi, Mar 30, 2011.

  1. NeuroChi

    NeuroChi is not his mind Staff Member

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    2-DPMP, or Desoxypipradrol, is a long acting stimulant drug that functions as an NDRI much like MDPV and Methylphenidate, the latter of which it is an analog of. Its effects include promoting wakefulness, attention, and arousal, however it can also significantly reduce ones ability to fall asleep due to its long duration of action.

    [h="1"]Introduction to 2-DPMP[/h]
    [imgr=white]https://www.drugs-forum.com/forum/attachment.php?attachmentid=22213&d=1314934448[/imgr]First discovered by CIBA pharmaceutical company (now refered to as Novartis) in the 1950s, 2-DPMP acts as a central nervous system stimulant by means of norepinephrine-dopamine reuptake inhibition. Upon its initial discovery, 2-DPMP was undergoing research as a possible treatment for narcolepsy and ADHD, however further research on the compound was cease upon the discovery of methylphenidate. 2-DPMP has also undergone research as a possible recovery agent for patients awakening from anesthesia, though trials were short and development did not continue.

    [h="1"]Using 2-DPMP[/h]
    [h="2"]Ways of administration[/h]
    2-DPMP has been proven to be active through a variety of different routes including oral, intranasal, sublingual, and intravenous administration. In terms of its recreational effects, 2-DPMP is most often administered through insufflation, due to its considerably high bioavailability (>90%).
    [h="2"]Effects of 2-DPMP[/h]
    [H="3"]Positive[/H]
    • Increased concentration
    • Stimulation
    • Euphoria
    [H="3"]Neutral[/H]
    • Nystagmus
    [H="3"]Negative[/H]
    • Insomnia
    • Anxiety
    • Tachycardia
    • Hypertension
    • Bruxism
    [h="2"]Combinations with 2-DPMP[/h]

    [h="2"]Different Uses for 2-DPMP[/h]
    • 2-DPMP has been investigated as a possible treatment for narcolepsy and ADHD, however research was dropped after the discovery of methylphenidate as the compound proved to be more promising than 2-DPMP.
    • 2-DPMP has also been researched as a possible recovery agent for patients awakening from anesthesia, though trials were short and development did not continue.

    [h="1"]Pharmacology of 2-DPMP[/h]

    Column 1 Column 2
    0 Mechanism of action NDRI
    1 Bioavailability >90%
    2 Half-Life 16-20 hours
    3 Metabolism Hepatic

    [h="1"]Chemistry of 2-DPMP[/h]
    Column 1 Column 2
    0 Systematic(IUPAC) name: (RS)-2-benzhydrylpiperidine
    1 Synonyms: Desoxypipradrol, 2-DPMP
    2 Molecular Formula: C[sub]18[/sub]H[sub]21[/sub]N, C[sub]18[/sub]H[sub]21[/sub]N.HCl (hydrochloride)
    3 Molar mass: 251.37 g/mol, 287.83 g/mol (hydrochloride)
    4 CAS Registry Number: 519-74-4, 5807-81-8 (hydrochloride)
    5 Melting Point: no data
    6 Boiling Point: no data
    7 Flash Point: no data
    8 Solubility: no data
    9 Additionnal data: none
    10 Notes: none


    [H="2"]Reagent test results of 2-DPMP[/H]

    Reagent color produced picture video
    1 Marquis Reddish[FOOTNOTE=1]http://www.reagent-base.net/reagents-table/[/FOOTNOTE] - -
    2 Mandelin Yellow/light green - -
    3 Mecke No reaction[FOOTNOTE=1][/FOOTNOTE] - -
    4 Cobalt thiocyanate Pink[FOOTNOTE=1][/FOOTNOTE] - -


    [h="1"]The dangers of 2-DPMP[/h]
    Prior to administering 2-DPMP one should review the potential dangers that are associated with the compound.
    • 2-DPMP is a research chemical, thus the effects and side effects of the compound have yet to be established due to a lack of formal trials.
    • 2-DPMP acts as a central nervous stimulants, user whom have a known physical illness should avoid this compound as it may result in dangerous and potentially deadly side effects.
    • 2-DPMP has a very long half-life, thus the drug has been know to stay active from very long periods of time especially when redosing occurs, resulting in several days worth of rather uncomfortable or annoying insomnia.
    • 2-DPMP is a psychoactive substance thus users whom have a known mental illness should avoid this compound as it may result in undesirable side effects.

    [h="1"]Producing 2-DPMP[/h]

    [h="1"]Forms of 2-DPMP[/h]

    [h="1"]Legal status of 2-DPMP[/h]
    [h="2"]United Nations[/h]

    [h="2"]USA[/h]

    [h="2"]EU[/h]

    [h="3"]Finland[/h]
    2-DPMP was listed as a narcotic drug without medicinal value as of late 2012.

    [h="2"]Other Countries[/h]

    [h="1"]History of 2-DPMP[/h]
    Popularity of 2-DPMP over time:

    [insights]2-DPMP[/insights]

    [h="1"]More 2-DPMP Sections[/h]
    2-dpmp / desoxypipradol trip reports
    2-DPMP / Desoxypipradrol Drug Info

    [h="1"]The latest 2-DPMP threads[/h]
    [showthreads=10]21[/showthreads]

    [CAT]Research Chemicals[/CAT] [CAT]Stimulants[/CAT][CAT]Piperidines[/CAT]

    [h="1"]References[/h]
    [REFLIST][/REFLIST]
     

    Attached Files:

  2. NeuroChi

    NeuroChi is not his mind Staff Member

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    Added an intro a while ago and a molecular image now.

    Could someone build effects and dangers information? This is a very long acting stimulant, I imagine high doses can pose serious threat to the cardiovascular system.
     
  3. Docta

    Docta Idiot Savant

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    New DF Wiki image (orientation correction)
     

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  4. pikhal

    pikhal

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    I am still a new member and unfamiliar with the ropes, but I have a good deal of info/chemistry/experience with this and quite a number of stimulant compounds listed on the DF site. How do I go about entering this information?
     
  5. hookedonhelping

    hookedonhelping Titanium Member

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    Please, pikhal, share share share as this is a rather interesting compound and I am sure a lot of us here would appreciate any input someone with experience surrounding the chemistry, synthesis and overall bio-activity/effects of the chemical.

    You could add the info you can here and I am sure if Alfa or another mod wants it elsewhere, they will move it for you. Thanks!
     
  6. NeuroChi

    NeuroChi is not his mind Staff Member

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    Drugs-Wiki Functionality describes how to edit the wiki, however, you must be a donating member or Titanium (or higher membership level) to do so.

    If you would like to type up sections of the wiki, you can post them here and another member can paste it to the wiki. This is a good way to gain reputation if your posts contain quality information and can result in membership upgrades, until you can post in the wiki yourself.
     
  7. syntheticdave

    syntheticdave

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    Hello added some info on this compound such as basic info, ways of admin, effects, different uses, pharmacology, chemistry, dangers, and legality
     
  8. John_bob

    John_bob Titanium Member

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  9. JTC3889

    JTC3889 Silver Member

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  10. Cykelrat

    Cykelrat Newbie

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    Nasty chemical, injected 150mg IV and was awake for 11 days.... Never ever again!
    Wasn't even a rush when I injected it.