Alkaloid Content of Mimosa Hostilis

Discussion in 'DMT and Ayahuasca' started by Guest, Apr 27, 2005.

  1. Guest

    Guest Guest

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    Does anyone have any information on an analysis of the alkaloid content of Mimosa Hostilis?



    Failing that, the % of n,n-DMT, 5-methoxy-n,n-DMT, 5-hydroxy-n,n,-DMT (bufotenin)?
     
  2. Dimitri

    Dimitri Gold Member

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    There should be just N,N-DMT in Mimosa Hostillis. As far as I know it is 0.57%.
     
  3. Guest

    Guest Guest

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    I doubt that the only alkaloid in Jurema is n,n-DMT. It maybe the only psychotropic one.....



    I'd like analysis that includes inactive alkaloids too. Basically, what
    % of a crystalline alkaloid extract will be n,n-DMT. Any information
    would be useful.



    Please could you include references too.



    I don't ask for much, honest [​IMG]
     
  4. transit

    transit Newbie

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    I just spent awhile looking in books and
    online for an answer to your question – no answers. </span>I am surprised. </span>It is an obvious and important question,
    though not one that I recall having seen addressed before.</span>


    I will be very interested in seeing if
    someone is able to offer an answer to this along with a reference. </span></span>
     
  5. Dimitri

    Dimitri Gold Member

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    Well, it is at the moment the only tryptamin alkaloid found in Mimosa,
    or at least the only one there is information about. Of course there
    CAN be more than just the N,N, It is even high propably that there is
    more, but nothing was found in the few analysis done. At least the
    one's I read about. So I guess you ask quite much for :)
     
  6. allyourbase

    allyourbase Palladium Member

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    there is some possibility of there being MAOI's. however theyre thought to exist only in trace amounts. it has no other alkaloids...perform an extraction, youll see potency is ~ that of fine grade synthetic.
     
  7. Guest

    Guest Guest

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    Has anyone got any first hand accounts of extracted Mimosa DMT vs. synthetic DMT?



    It's a long shot........
     
  8. DrugPhreak

    DrugPhreak Gold Member

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    There is no life formon this planet thatcontains onlyone alkaloid. Also, I've never readany data, whichstatesMimosa Hostilis rootbark contains B-Carbolines. If it did oral consumption wouldn't be an issue of course. Although,pulling the freebase with halogenated hydrocarbons can partially convert some of the alkaloids (including DMT) into B-Carbolines in high amounts via Pictet-Spengler.Edited by: DrugPhreak
     
  9. indjuwandjuwa

    indjuwandjuwa Newbie

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    DrugPhreak - I did read somewhere on the net- information from Jonathan Ott - that there is a substance in the rootbrk - maybe not a B-carboline - that inhibits the amine in the rootbark from being broken down. J Ott is the MH master , me thinks.
     
  10. Eirias

    Eirias Gold Member

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    .

    Edited by: Eirias
     
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  11. Eirias

    Eirias Gold Member

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  12. DrugPhreak

    DrugPhreak Gold Member

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    I can't access any literature where I live right now, but have a look atthis. After doing an A/B with DCM 2-Methyltetrahydro-b-carboline was found at~10% by weight. I see that the Phytochemistry reference states that Phalaris Arundiaceadoes in fact contain this substance, but maybe there is Mimosa somewhere that contains it (or a similar substance) also. [​IMG]This substance is a metabolite of DMT so it may be that some people metabolize thisMAOIto a greater extent than other people for some reason. [​IMG]


    This is also an interesting threadthat deals with Trichocereus Peruvianus.Edited by: DrugPhreak
     
  13. Eirias

    Eirias Gold Member

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    Wow. He doesn't clarify this point, but I am assuming that
    he obivously used the rootbark</span>, </span></span>and not some other part of the plant as his initial source material. And
    it remains a mystery whether it is a result of that sneaky
    Pictet-Spengler rxn brought on by the halogenated hydrocarbon nonpolar
    i.e. DCM, or if it in fact it's found in the initial plant material to
    begin with. This question could be straightened out a bit if
    he/she (or whomever) was to do another Mimose Hostilis Rootbark extraction with a
    non-halogenated NP solvent like the traditional naphtha and then
    perform the chromatography.

    If it is indeed found in the rootbark naturally, then Ott's
    theory I cited, about various DMT adducts competing with the primary n,n-DMT for
    MAO enzymes in the digestive tract as being the source of
    Jurema's "neat" activity in humans (i.e. no MAOI adjunct plant is
    needed) is possibly incorrect, due to this newfound b</span>-carboline
    factor. Yet in the reference of Ott's I linked to above, he states
    that approximately five mostly unpublished analyses of Mimose Hostilis Rootbark alkaloid
    profiles have failed to show the presence of any MAOI-like
    beta-carbolines.

    Is is really possible that Ott, or whomever else
    performed these Mimose Hostilis Rootbark analyses was so careless or poor in his/her
    methodology as to overlook something so seemingly obvious? 10% of
    the whole alkaloid profile is hardly "trace", and to me the data
    DrugPheak has brought up coupled with the Ott reference suggest that in
    fact the detected presence of beta-carbolines in the aforementioned
    experiment is indeed a result of a reactionary mechanism, most likely
    Pictet-Spengler.

    If anyone has hypothetical access to synthetic or otherwise
    98-99%+ pure n,n-DMT, then please consider the potential experiment of
    comparing that substance with the extracted and purified crystalline
    "DMT" alkaloid product as is derived from M. hostilis rootbark, with the intention as to determine
    any subjective idiosyncracies. A futher experiment could be
    conducted ala Gracie & Zarkov</span>, involving the smoking of n,n-DMT
    with b</span>-carbolines and then comparing this to the Mimose Hostilis Rootbark DMT product.

    G & Z's experiment I mentioned is titled something like
    "Three Beta-carboline Containing Plants as Possible Potentiators of
    Smoked DMT", and the plants they use are Passiflora incarnata, Peganum
    harmala, and Banisteriopsis caapi. .

    Edited by: Eirias
     
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  14. DrugPhreak

    DrugPhreak Gold Member

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    Yeah, I wouldlove tosee theGC/MScomparisons between an A/B where the freebase was pulledwith DCM and other non-halogenated solvents. Also, I wish they did an oral bioassay. I have tried to contact this person, but theyno longer post on that forum. Is anyone in contact with them or know if they are posting on another board? If so please send me a PM. If I ever found a way to get a GC/MS I would burn that sucker out in no time. [​IMG][​IMG]<?:namespace prefix = o ns = "urn:schemas-microsoft-com:eek:ffice:eek:ffice" /><O:p></O:p>Edited by: DrugPhreak
     
  15. raven3davis

    raven3davis R.I.P. Palladium Member R.I.P.

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    Is it possible to have bark that is 2%? I wass reading in some forums, and people were saying they could get like 1.5grams of DMT from only like 1/4lb or something like that. That seems unbelieveable to me.
     
  16. Marsofold

    Marsofold Platinum Member

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    I don't believe it either. "Experts" don't bother with quarter pounds...
     
  17. Dimitri

    Dimitri Gold Member

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    I was wondering about the same. I guess what they get is NaOH or other impurities in their final crystals.
     
  18. Eirias

    Eirias Gold Member

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    .
    The only situation I could imagine in which the Mimosa rootbark would
    yield anywhere near that high would be if it was "high quality inner"
    rootbark of an already potent strain. This is still speculation
    on my part nonetheless. It seems like the Mimosa rootbark is much
    more consistent in its alkaloid profile and content than nearly any
    other DMT-containing plant material, especially green leafy sources
    like Phalaris and Psychotria.
     
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  19. MegaLab420

    MegaLab420 Newbie

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    If you put in as much effort to extracting the stuff, you could synthesise it!


    I have extracted DMT years ago from MH root bark and the process took 2 days and was extreeeeemly messy. Not to mention I broke a brand new blender and ended up with 1 whopping dose.


    Pshhh, I feel ashamed looking back on the time I wasted.
     
  20. MegaLab420

    MegaLab420 Newbie

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    Ok, well maybe it's not that easy to synthesise.. (after reading my opening statement) But the extraction is alot of work for little reward. Not to mention cost..