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Tolerance - Amount of grapefruit juice and its affects

Discussion in 'Opiates & Opioids' started by blueflame128, Feb 5, 2009.

  1. blueflame128

    blueflame128 Newbie

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    Oct 27, 2007
    Male from U.S.A.
    So little Johny Doe down the road asked me an interesting question the other day...

    He knows that drinking grapefruit juice 1/2 hour before taking your opiate will potentiate the effects. He said he usually just drinks a glass, but he was wondering what would happen if he drank nothing but 100% pure grapefruit juice all day, and then took his normal dose. Does the amount of juice drank affect how much it will potentiate your hydro or whatever?:crazy

    MEKONE Silver Member

    Reputation Points:
    Oct 8, 2007
    Male from U.S.A.
    As SWIM said in another post he drinks GFJ all day like if it was water.In fact water and GFJ is all SWIM drinks all day as he really likes the taste of it.SWIM can say for sure there is a diffrence in how much GFJ is drank and he can say that his effects last a bit long and a bit harder than if he were to drink just water.

    Awhile ago SWIM drank his meds W/O GFJ and can honestly say that he DID feel mild W/D's,so there is a connection to this and it may be due tothe amount of GFJ SWIM consumes daily.
  3. Creeping Death

    Creeping Death Iridium Member

    Reputation Points:
    Jun 29, 2004
    SWIM once ate a whole grapefruit after his buprenorphine buzz started to fade away. It was delicious, and it made SWIM start nodding again as he did in the peak of the buzz. And the more swim ate, the more he felt.

    So yes, for SWIM it has worked very well. Maybe it works even better if you eat it than if you drink it.
  4. Matt The Funk

    Matt The Funk Silver Member

    Reputation Points:
    Sep 9, 2007
    Male from U.S.A.
    SWIM use to drink GFJ all day to help potentate all his DOC's and he thinks it worked really well. SWIM realized how much more $$ efficient it was, and didn't stop till it became too much to keep buying GFJ all the time (annoying). SWIM thinks after a certain amount being drunk it probably won't make much of a difference, but a few glasses will help potentiate, anything after that SWIM thinks just keeps that high potentation going, but to be honest he isn't sure of the exact pharmalogical effects.

    EDIT: SWIM isn't sure about how long the GFJ lasts....he understands how it works.
    Last edited: Feb 14, 2009
  5. drgreenthumb881

    drgreenthumb881 Newbie

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    Dec 23, 2007
    Male from earth
    Swim uses either one glass of 100% grapefruit juice, or eats one whole fresh grapefruit, and always waits 1 full hour. The fresh fruit is better in swims opinion, especially since in the north bronx really good ruby red grapefruits are 4 for a dollar. As far as swim knows, the grapefruit inhibits an enzyme in the liver (cy-pd 24) or something like that lol, the name might not be exactly correct, but thats def. what happens, and it slows down the metabolization of said d.o.c.'s, but it also does the same for acetaminophen/paracetamol, so be careful, i hear excess of those two can cause liver damage after many years, swim rarely consumes alcohol therefore doesn't worry about it. Hope this helps. peace, swiDrGreen
  6. Spucky

    Spucky Palladium Member

    Reputation Points:
    Feb 9, 2009
    Male from japan
    AW: Amount of grapefruit juice and its affects

    People have to be very carefull,
    some People already lost their lives,
    special in the combination with Methadone and other strong Opioids.
    The serum-level will increase uncontrollable.
    Ever Pack of Juice is different from the other!