Baclofen (brand name Lioresal, Kemstro) is a GABA-B agonist used as a muscle relaxant in multiple sclerosis. I've long been interested in this drug for several reasons: muscle relaxers often have some type of abuse potential, it is a GABA-B agonist and the benzo's, barbs and Ambien-type drugs are GABA-A agonists, and it is an analogue of the popular drug GHB. I finally decided, after much research, that I must try it. Several weeks ago I ordered fifty baclofen 25 mg tablets from a commercial source. Upon recieving the package I immediately went to work. My initial experience was profoundly intense, so much so that I would consider it adversive. This was probably do the excessive dose I had ingested over the course of the day (325 mgs in a 18-hour period). The initial effects weren't apparent after 75 milligrams, so another dose of 75 milligrams was taken to produce mild dizziness. It still didn't feel like much of anything so a third dose of 75 milligrams, bring the total amount to 225 milligrams, was taken with water. Wow. Again, wow. The effects manifested themselves without being shy about it. That feeling of dizziness multiplied to a feeling of clumsiness, but not an unpleasant clumsiness. It was strangely similar to the "buzzing" of alcohol intoxication, but there were unique aspects that are hard to describe. My mood was enhanced, yet I wasn't euphoric to manic proportions as he is on amphetamine or opiates. It was an antidepressant-like mood-enhancement. Words weren't slurred and coordination was in tact roughly 75-80%. After interacting with my family for a while the intensity of the "buzzing" dizziness became too much and I went to go lay down. I turned the TV on and put my head down on my bed with a pillow covering it. This was at approx. 1:30 PM. After what seemed like a half hour, I sat up and a wave of disbelief swept over my body when I looked over at the window. It was dark outside! Not twilight-dark, I mean middle of the night dark. I stumbled upstairs and stared in awe at the digital clock: it read 12:45. It was forty-five minutes after midnight and I had just lied down a half-hour ago, it seemed. I suddenly became nausious and went downstairs, only to end up vomiting on my patio. I laid back down after that. I was in for an unbelieveable experience but I didn't know it at the time. It was a dream, I know that now. But while it was happening, it wasn't a dream. It was to real to be a dream. I had suddenly found myself driving down a road, cornfields on both sides of me. My car was missing everything but the wheels and a metal bar in-between the front and back axels. The sun was shining; it was probably 11 in the morning. A cop was in the process of writing a speeding ticket to a car on my right. I was high as can be. All of a sudden I was upstairs in my friend's house, alone, smoking pot. I looked out her window; it was night. I thought to myself "man, I'm really flipping high. I hope ********'s parents don't come up here." And then, I woke up. It was more like I sprung out of bed. I was dreaming! I couldn't believe how real the dreams had been. I was actually feeling high in the dream, I could actually feel the sun on my skin when I had been "driving", and I felt actual fear of her parents catching me... yet it was only a dream? What is this stuff, I asked myself. I took 50 milligrams after waking up; this was approx. 11:30 in the morning. The dizziness was apparent, only it was different this time. It was more enjoyable. It felt like psychedelic Xanax, so to speak. My mood was enhanced, only greater than it had been the day before. My body felt nice, where yesterday it had felt "weird" in a bad way. This is the way it's been ever since that morning. It took an initial adversive experience to become familiar with the drug and it's effects, sort of like first-time marijuana users usually don't get high on their first experience because they have to become familiar with marijuana's effects and learn to find them pleasurable. This is why experienced smokers report more intense effects than inexperienced smokers: their brains have learned that marijuana is indeed psychoactivly euphoric. Baclofen has very similar properties. I hope this look into the somewhat-obscure drug baclofen is at least an interesting read!