1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP
    Dismiss Notice

Combinations - benadryl (Diphenhydramine) + hydrocodone

Discussion in 'Deliriant antihistamines' started by RobJaw, Sep 11, 2008.

  1. RobJaw

    RobJaw Newbie

    Reputation Points:
    -14
    Joined:
    Jun 5, 2007
    Messages:
    48
    Hydrocodone + Diphenhydramine

    Swim found a note that said the combination hydrocodone + Diphenhydramine can cause the opiate buzz to feel stronger and better. Swim was wondering if this is true? :cool:

    Thanks!
     
  2. PilL FreaK

    PilL FreaK

    Reputation Points:
    75
    Joined:
    Mar 23, 2008
    Messages:
    31
    Re: hydrocodone + Diphenhydramine (?)

    When SWIM tried Diphenhydramine on its own it was pretty intense and he got spasms in his legs.. When he laid down his legs kept kicking up. I wouln`t try that combination.
     
  3. fiveleggedrat

    fiveleggedrat Palladium Member

    Reputation Points:
    1,180
    Joined:
    Nov 28, 2007
    Messages:
    2,001
    Re: hydrocodone + Diphenhydramine (?)

    At low doses, as in, under 50mg, some have reported increased CNS sedation and similar, but decreased itching.

    Anything over 100mg is asking for a delirious, lousy opiate high.
     
  4. Zaknafien

    Zaknafien

    Reputation Points:
    -4
    Joined:
    Sep 4, 2008
    Messages:
    22
    Re: hydrocodone + Diphenhydramine (?)

    how much hydrocodene would swim have to take in combination to receive the increased high and how strong is the high? A quick answer would be appreciated as swim intends on doing this soon.
     
  5. fiveleggedrat

    fiveleggedrat Palladium Member

    Reputation Points:
    1,180
    Joined:
    Nov 28, 2007
    Messages:
    2,001
    Re: hydrocodone + Diphenhydramine (?)

    Take a little less than usually. Just use common sense when dosing. If you make a dose of say, 40mg stronger, you might want to reduce it to say, 30mg. Personal preference comes in here too.
     
  6. Zaknafien

    Zaknafien

    Reputation Points:
    -4
    Joined:
    Sep 4, 2008
    Messages:
    22
    Re: hydrocodone + Diphenhydramine (?)

    haha good lord 30mg? Swims at 15mg ^.^. And is the high alot different then each by its self? cause swim don't much like diph all that much but hydrocodien he does.
     
  7. RobJaw

    RobJaw Newbie

    Reputation Points:
    -14
    Joined:
    Jun 5, 2007
    Messages:
    48
    Re: hydrocodone + Diphenhydramine (?)

    a note from ganny said this "

    SWIM tripped so hard last night. SWIM did a 30 mg and about 800 diph... omg.. It was scary cause SWIMS dad was yelling at SWIM and telling SWIM to get out of the house and the ride is on its way to come pick me up! it was so freaken real... so SWIM went to my bedroom so depressed haha... and a few hours ago I found out that my dad was here a week ago... and my mom didnt even talk to me last night... but OMG They totally freakn did if you know what SWIM means. BTW Swim realized that the DRUG becomes magic at night! In the day time its not so trippy but when the sun goes down!!! OMG!! "
     
  8. purplehaze

    purplehaze Gold Member

    Reputation Points:
    1,229
    Joined:
    Jan 28, 2005
    Messages:
    1,262
    Re: hydrocodone + Diphenhydramine (?)



    This is the thread you want.
    http://www.drugs-forum.com/forum/showthread.php?t=10884&highlight=potentiating+opiates
     
  9. cra$h

    cra$h Silver Member

    Reputation Points:
    1,171
    Joined:
    Oct 21, 2007
    Messages:
    2,450
    Gender:
    Male
    Location:
    PA
    Re: hydrocodone + Diphenhydramine (?)

    a lot of people will pop a benadryl (diphenhydramine) or 2 with opiates to get better nods, and stop the itchies. It does stop the itchies though, as long as the dose (of diphen) is low.
     
  10. ~lostgurl~

    ~lostgurl~ Platinum Member & Advisor

    Reputation Points:
    3,442
    Joined:
    Dec 23, 2004
    Messages:
    3,971
    Re: hydrocodone + Diphenhydramine (?)

    Diphenhydramine is known to cause/worsen Restless Legs Syndrome (RLS) in those who suffer from it or are prone to it. This girl I know found diphenhydramine seriously worsened her RLS but only while on it, the next day she was fine.

    Combining it with hydrocodone might actually reduce or cancel out the RLS as opiates are often used to treat it.

    For most people RLS is not an issue though. Pill Freak, I would suggest getting your iron/ferritin levels checked and if these are fine and you have more frequent issues with your legs then do some research into RLS as it is a complicated illness.
     
  11. RobJaw

    RobJaw Newbie

    Reputation Points:
    -14
    Joined:
    Jun 5, 2007
    Messages:
    48
    Re: hydrocodone + Diphenhydramine (?)

    SWIMS has tested this and the combo does make it much Funner! and there is almost no restlessness at all!

    2 x Norco 7.5 with about 800 mg diph
     
  12. fiveleggedrat

    fiveleggedrat Palladium Member

    Reputation Points:
    1,180
    Joined:
    Nov 28, 2007
    Messages:
    2,001
    Re: hydrocodone + Diphenhydramine (?)

    That has to be a joke.
     
  13. RobJaw

    RobJaw Newbie

    Reputation Points:
    -14
    Joined:
    Jun 5, 2007
    Messages:
    48
    Re: hydrocodone + Diphenhydramine (?)

    Note from Grandma ol'roy

    Negative! SWIM believes some people can do this... others can't. When SWIM first did this... SWIM did get very restless it was un-enjoyable... but over time SWIM has to make do... with what SWIM can get sadly... Especially latly because SWIM was in a horrible accident and now SWIM has 16 screws and 3 plates in SWIMS hip along with a broken lower back.
     
  14. fiveleggedrat

    fiveleggedrat Palladium Member

    Reputation Points:
    1,180
    Joined:
    Nov 28, 2007
    Messages:
    2,001
    Re: hydrocodone + Diphenhydramine (?)

    Why in the world would someone take 800mg? Most people get delirious off 300mg, not to mention the unpleasant side effects of antihistamine overdose.

    Anything over 75, perhaps 100mg is completely pointless for increasing the effects of the opiate.
     
  15. tryptamaster

    tryptamaster

    Reputation Points:
    -51
    Joined:
    Jul 12, 2008
    Messages:
    488
    Re: hydrocodone + Diphenhydramine (?)

    yea dude ur "trippy" effects were jsut a fucked up delerious high. thats liek drinkin 30 beers to potentiete 1mg clonazepam. ur jsut gonna be drunk haha.
     
  16. spaceyjake

    spaceyjake Newbie

    Reputation Points:
    0
    Joined:
    Dec 22, 2008
    Messages:
    3
    Re: hydrocodone + Diphenhydramine (?)

    swim just tried out this combination and so far it is working out really well
     
  17. adamm92

    adamm92

    Age:
    28
    Reputation Points:
    0
    Joined:
    Nov 25, 2008
    Messages:
    11
    Re: hydrocodone + Diphenhydramine (?)

    You're not tripping from the hydrocodone, you're tripping from the benadryl!!! Benadryl is a deleriant like datura!!!
     
  18. RaverHippie

    RaverHippie Gold Member

    Reputation Points:
    2,184
    Joined:
    Nov 7, 2007
    Messages:
    2,221
    Re: Hydrocodone + Diphenhydramine

    Again, this combination is meant as a recommendation for a small amount of diphenhydramine (max 50mg) to increase the potency of someone's normal opiate dose. That is the general consensus and is usually discussed in the opiate forum like the link that purplehaze mentioned.

    Now, RobJaw is onto something interesting since the more awful parts of the deliriant high include the RLS-like symptoms which Lostgurl mentioned. If a recreational dosage of diphenhydramine (300mg+) is combined with an opiate of some sort, possibly the deliriant high will be even more enjoyable than it currently is for many users.
     
  19. Black_glowsticks

    Black_glowsticks Newbie

    Age:
    25
    Reputation Points:
    1
    Joined:
    Jun 3, 2010
    Messages:
    6
    So Swim is sitting in the bathroom looking for a trip, but at least 4 hours ago probably 5 swim took a normal dose of hydrocodone that was crushed and drank. Would it have any adverse affects on swim if swim took 250mg of diphenhydramine? Also swim was wondering if 250mg is to much or to little for first recreational use.


    Also sorry swim is a newbie and this is swim's first post, swim has been lurking without an account for ages.
     
  20. stormchasar

    stormchasar Newbie

    Reputation Points:
    0
    Joined:
    Apr 14, 2010
    Messages:
    52
    Re: benadryl + hydrocodone

    Diphenhydramine mixed with depressants doesn't have the risks associated with stronger hypnotics, at least not that I know of. Alcohol consumption before taking diphenhydramine is reported to increase its potency, but it's probably not dangerous otherwise.
    Honestly, you'll probably just fall asleep.