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benzodiapine urinalysis, can you differentiate between different benzos?

Discussion in 'Drug testing discussion' started by really long nipples, May 11, 2011.

  1. really long nipples

    really long nipples Newbie

    Reputation Points:
    Apr 10, 2011
    33 y/o Male from U.S.A.
    I know different benzos produce different metabolites, so if I have a gs/mc urinalysis xanax would show up differently than temazepam.

    my question is, are there any benzos that would mimic the way temazepam appears on a drug test?

    i.e. lets say midazolam produced the same metabolites (which I don't think it does, and I took both midazolam and temazepam, if the drugs mimic each other you would not be able to differentiate on drug tests.

    I am trying to find anythign that shows up the asme as temazepam.
  2. Mr. Jiki

    Mr. Jiki Titanium Member Donating Member

    Reputation Points:
    Dec 2, 2010
    Male from U.S.A.
    Yes. Temazepam metabolizes to oxazepam. Oxazepam is also a metabolite of diazepam and chlordiazepoxide. Diazepam will actually metabolize into temazepam and then into oxazepam.

    Midazolam doesn't share the same metabolites as Temazepam. Its metabolites are 1-OH-midazolam, 4-OH-midazolam and 1,4-di-OH-midazolam.

    This is a leb dependant variable in trying to have drugs with the same metabolites. Ru's lab used to test for oxazepam (but not temazepam/chlordiazepoxide/diazepam), so they'd call all diazepam, temazepam and chlordiazepoxide medication consistent with the positive results. They have since added diazepam to their confirmation test.

    So, if the lab where the UA is being sent only tests for oxazempam, among others, and doesn't check for metabolites for chlordiazepoxide or diazepam, SWIY could take either of those drugs and explain why that result was there with whatever drug they were taking. I'm not sure how many labs test for midazolam, but if they did, they would be able to tell the difference between the two.
  3. Chris70509

    Chris70509 Newbie

    Reputation Points:
    Dec 8, 2011
    Male from U.S.A.
    This is correct, I spoke with an MRO for a large drug testing company and was told they can not distinguish between either one.