I've started a brain biology class recently and was reading through the text book about opiates. I found that opiates produce euphoria by inhibiting the release of gaba and therefore increasing levels of dopamine. Benzos need gaba to work since they increase gaba's affinty for gaba'a receptors. Shouldn't opiates cause benzos to cease function then? This was just a little thought, since everyone says opiates and benzos mixed can be oh so deadly.