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Drug info - Bremelanotide?

Discussion in 'Various drugs not covered by other forums' started by Mick Mouse, Jan 3, 2011.

  1. Mick Mouse

    Mick Mouse Palladium Member

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    Has anyone heard of Bremelanotide (a.k.a. PT-41)?

    It seems to belong to a new class of drugs called melanocortids and is on track to become the first FDA-approved aphrodisiac. Currently in the last stages of preclinical trials for said approval (as of 2009).

    It is not an ED drug or PDE-5 inhibitor, but seems to work by activating hypothalamic and limbic emotional structures in the brain.

    It seems to work equally well on both men and women. However, there are instances of side effects, some men report a rise in blood pressure and about 1/3 of the women who tried it reported nausea.

    It is available on the web via legit pharma companies, but, if interested in this, I'm sure you can find it without me giving you web-sites! You CAN, however dig up more info on this by researching Jim Pfaus, a neuroscientist out of Montreal or Mohammad Reza Safarinejad, An Iranian urologist.

    Pfaus has 1300 anonymous testers in 2006 and the drug went into phase-three testing in 2007.

    I haven't heard anything about it since.
     
  2. veritas.socal

    veritas.socal Silver Member

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    wow,bro. an FDA approved aphrodisiac? i havent checked it out yet, but i will. for sure
    do you know if this is approved as an aphrodisiac, or is this an off-label usage??(ie tegretol is for seizures, but prison MDs RX it for pain,headaches, etc. gabapentin is for seizures, but still rx for nerve pain/burning, as well as depression and headaches.)
    namaste
     
  3. Mick Mouse

    Mick Mouse Palladium Member

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    Originally developed as (are you ready for this?) a self-tanning agent! It was repurposed when male study subjects reported a surprising side effect: erections. Fairly amazing erections! Whoda thunk it?
     
  4. Terrapinzflyer

    Terrapinzflyer MDMA, RC & News Forums

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    hmmm- according to wikip the info in this thread is somewhat off. (and while wikip is not a definitive source the info does seem to fit with what I am seeing elsewhere).

    And regardless- to answer the original question it appears to be be stuck in negotiations with the FDA over the blood pressure issue.


    Iupac Name:(3R,6R,9S,12R,15R,23R)-15-{[(2R)-2-
    Acetamidohexanoyl]amino}-9-benzyl- 6-(3-carbamimidamidopropyl)-12- (1H-imidazol-5-ylmethyl)-3-(1H-indol- 3-ylmethyl)-2,5,8,11,14,17-hexaoxo- 1,4,7,10,13,18-hexaazacyclotricosane -23-carboxylic acid

    CAS number: 189691-06-3

    Formula C50H68N14O10


    and an article from 1999 at CNN on its parent drug Melanotan
    HERE

    I've also attached a so called "fact" sheet from Palatin- the pharmaceutical company that was/is developing this.


    And finally- moving this to "Various drugs" forum...
     

    Attached Files:

  5. Mick Mouse

    Mick Mouse Palladium Member

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    Thanks! Great follow-up and good info/links for further research. My original info came from an article in a Mens magazine dated September 2009, so I wasn't too sure of its accuracy. I actually thought I UTFSE on this, but it appears I didn't. Duh! Too many things going on at once!
     
  6. Boca Bitch

    Boca Bitch

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    Hmm... I'm wondering the potential for abuse with this substance. If it works on the CNS, as opposed to just increasing erection duration or ability (such as Viagra)... it could then be used in people who don't necessarily need the substance with some degree of success, yes?

    Would this be the new "ecstasy" for young couples? Or would it be the new "Rohypnol"? ;)

    ... if anything at all.