I was on Effexor XR and worked up from 37.5mg to 150mg a day and my doc is having me tapper down, mainly due to the cost and my ins will not cover a non generic med and im not paying 300 dollars a month for 30 pills ... I am not on Celexa 20mg, im still tapering down and only have 3 days left on 37.5 effexor before my taper is done and the last 3 days ive cut my celexa in half and was taking 10mg and the effexor and didn't have any neg side affects. ok enough of my current 2 week history, now my questions and some more history of SWIM. .. I am also taking, Kadian 30mg time release which he normally crushes up and takes either by insufflation :snort: , and tried rectal administration as well as oral but since morphine is more bioavailable insufflated and rectally is desired. I am also taking Hydro/Oxycodone a couple times a week to keep tollerence levels down, taken orally(< for the most part, I also have scripts for everything listed above for a workcomp injury. ------ so now that I am taking Celexa, what should he know about it. I want to know if there is complications with anythingelse, like what was listed above. I am also a daily cannabis user :smoking:,a legal user of cannabis and hasn't felt any neg affects, I did notice neg affects with cannabis and Effexor XR only during the first two weeks it would spike My blood pressure. SWIM worries about SSRI's and feels like they can be much more dangerous if abused so I have never abused them and takes them for depression/aniexity disorders. I did a search for Celexa/Citalopram and did not come up with many results and much info at all.