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Drug info - Chlorpheniramine

Discussion in 'Deliriant antihistamines' started by mynameisshaun, Jan 27, 2005.

  1. mynameisshaun

    mynameisshaun Newbie

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    I recently got prescribed 120 TEAspoon bottle of Histussin. I read that
    it contains Chlorpheniramine Maleate as an active ingredient... Im
    wondering if this is like DXM and how much of it i would have to drink
    to start tripping out... I usually drink a 10 oz of DXM when i want to
    trip, just to let you know.



    thank you,

    shaun [​IMG]


    </font>
     
  2. Curtains

    Curtains Silver Member

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    Know how we tell people not to take Coricidin becuase its dangerous well thats becuase the other active ingredent in it is 4mg of Chlorpheniramine Maleate...... general is very dangerous to take in large doses with dextromethorphan. chlorpheniramine maleate is also metabolized by the same liver enzyme as is DXM. Which causes a competition for this limited enzyme by the two drugs

    ADVISE: use as directed not recreational becuase basicly all u got there is Coricidin, and we all no not to take CCC's
     
  3. RoboCop

    RoboCop Platinum Member & Advisor

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    NO do not drink that, it is not like dxm. That is the most dangerous chemical in all of cough syrups. It can cause heart problems, seizures, bleeding from just about every oraphace you can think of, liver damage, and fatalities. That is the last thing you want to drink. If you want to experiment with dxm go to your local store and pick up some tussin cough, dxm only.
     
  4. club222

    club222 Newbie

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    Don't drink it.
     
  5. mynameisshaun

    mynameisshaun Newbie

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    well, im probably going to, just to see what exactly it does, sorry for
    being stubborn.. im gonna drink half, and then wait an hour or 2, if nothing happends, i'll just drink normal doses from then on
     
  6. HippieD9

    HippieD9 Gold Member

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    Are you nuts?!? For once I'm at a loss for words... I know, next try drinking gas, I've heard that will get you high too [​IMG]You've been warned that something is deadly, and you still want to drink it even though it's not psychoactive? Have fun in the hospital! Don't hold yer breath for flowers though...





    D.
     
  7. yajw

    yajw Newbie

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    Chlorpheniramine Maleate is an antihistamine, whereas Dextromorphan is an anti-tussive.



    It's just a bottle of Chlor-Trimeton. Just like drinking a bottle of Benadryl.



    Now if it was Histussin-HC, well that would be somethign a little different.



    Wonder how long before he falls asleep?



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  8. RoboCop

    RoboCop Platinum Member & Advisor

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    After my post he still wanted to drink it....I don't understand people. I guess I should of just told him it won't get him high lol, that makes him not want to do it, while the whole oraphace bleeding and health problems doesn't phase him [​IMG] tsk tsk.
     
  9. HippieD9

    HippieD9 Gold Member

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    People obviously don't care about side effects anymore, have you seen all those drug commercials on TV?!? Favorite side-effect, "temporary heart failure" Yeah, I want that one!





    Peace,


    D.
     
  10. yajw

    yajw Newbie

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    He was already planning to do it, just wanted some kind verification.



    RoboCop, I did like your answer though. I assumed it was sarcastic, but
    I may have been wrong. If you were serious, were you thinking of the
    old formulation with phenylpropalalamine and bromipherimine.



    Chlorpheniramine is relatively safe. It's when some person thinks it's
    cool to mix it with another substance that utilizes the same enzyme to
    break down the chemical.



    But bleeding out your orifices may make you look hardcore to your friends sucking down the cough syrup. Who knows.
     
  11. RoboCop

    RoboCop Platinum Member & Advisor

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    Umm no sorry your wrong Chlorpheniramine Maleate is safe at the recommended dosage on the bottle, and that only. If you take to much, in other words over dose on it, (by this I jsut mean taking to much) it is very dangerous even alone. This stuff has cause fatalities, serious internal bleeding, etc. It is NOT safe to take to much of, read up on it.
     
  12. par excellence.

    par excellence. Newbie

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    Can Chlorpheniramine M. cause nose bleeds (if it's in a pill that you
    crushed into a fine powder and snorted)? Because once I snorted about 3
    or 4 pills with Chlor. M. as one of the ingredients and I had a
    continuous nose bleed for a couple of days...
     
  13. serotonin

    serotonin Newbie

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    it might not be the Chlorph. M. that's responsible for those nosebleeds. it might be snorting something that is clearly not ment to be put up one's nose.
     
  14. yajw

    yajw Newbie

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    Ok, you may have something there. But do you have any cites for
    Chlopheniramine Maleate toxicity or deaths by itself? Chlorpheniramine
    is considered the least toxic of the histamine agonists. Yes, you can
    overdose on everything, and people do. But every death or toxicity
    report that mention Chlorpheniramine via Pub-Med, or other journals do
    not list Chlorpheniramine as the responsible agent.



    There has been a link between alcohol and chlopheniramine since 1974,
    and the dangerous effects. Same with alcohol and all anti-histamines or
    CNS depressants. All reported overdoses have been with cold
    preparations that have a combination of dextrmorphan or guaifenesin, a
    decongestant (pseudoephedrine or PPA),alcohol and chlorpheniramine. So,
    you generally have 1 or 2 highly dehydrating agents, in extremely high
    doses, and subsequently a large dose of chlorpheniramine, all trying to
    be broken down by the same liver enzyme. It's not the chlorpheniramine
    doing the majority of damage.
     
  15. Paracelsus

    Paracelsus Platinum Member & Advisor

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    Chlorpheniramine - Active Dose?

    Chlorpheniramine maleate is present in many preparations, at doses around 2-5 mg, sometimes as an antihistamine, other times as a poison in order to discourage abuse of certain preparations (DXM-containing, Ephedrine-containing).

    I have searched for a dose-response study (or similar) for chlorpheniramine, but without many results.

    Does anybody have information about chlorpheniramine dose & effects? SWIM doesn't want to use it recreationally, but he wonders what effects (both physical and psychological) are to be expected with different dosages of chlorpheniramine (e.g. in a preparation).

    Thanks in advance.
     
  16. Elf Salvation

    Elf Salvation Newbie

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    Re: Chlorpheniramine - Active Dose?

    Chlorpheniramine maleate as in CCC's is very dangerous.

    Swim could only tolerate 12 CCC's max. People hit themselves in the face ect.
    Its a very vulgar and brutal way to get high.
    Not funn
     
  17. Paracelsus

    Paracelsus Platinum Member & Advisor

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    Re: Chlorpheniramine - Active Dose?

    12 CCC's max? Is that 12x4=48mg CPM?

    SWIM just wants to know in what doses the effects get noticeable. So he can figure how much is acceptable.
     
  18. Micklemouse

    Micklemouse Platinum Member & Advisor

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    Re: Chlorpheniramine - Active Dose?

    I do not think that using CCC's as a benchmark is that wise an idea folks - would the effects of the chlorpheniramine be discernible from the dxm?

    Please move away from discussion of CCC's if possible & stick to chlorpheniramine.
     
  19. Forthesevenlakes

    Forthesevenlakes Newbie

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    Re: Chlorpheniramine - Active Dose?

    SWIM hasn't had pure chlorpheniramine, but he can say, from using various cough syrups in the reccomended doses for colds and flus, that chlorpheniramine seems to be active at 2-4 mg for SWIM. It results in a detached, dreamy state where sleep is not far off. Some CEVs usually result before SWIM sleeps, if he closes his eyes for a couple of minutes. SWIM is guessing that these effects are not due to DXM or other ingredients present, since the amount of DXM in these preparations would be in sub-psychoactive doses for SWIM when taken as directed. Not really much in the way of euphoria, but SWIM did notice some greater degree of free association in thought when he tried to write after taking CPM. Overall though SWIM wouldnt really reccomend this drug for any sort of recreational use, the liklihood of dangerous effects in higher doses is too risky.
     
  20. AntiAimer

    AntiAimer Newbie

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    Re: Chlorpheniramine - Active Dose?

    Chlorpheniramine maleate is a antihistamine, so you can only guess it has some type of dissociating effects. Maybe hints why some actually prefer the evil CCC's even after knowing the evils. Taken from erowid...