1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP
    Dismiss Notice

Health - Clonazepam prescription running out, question about buying online

Discussion in 'Benzodiazepines' started by neverspeakagain, Aug 20, 2010.

  1. neverspeakagain

    neverspeakagain Silver Member

    Reputation Points:
    17
    Joined:
    Feb 10, 2010
    Messages:
    40
    31 y/o
    Hi everyone, swim is in desperate need of help here. It would be much appreciated.

    Swim is prescribed clonazepam 3mg/day for GI muscle spams for a horrible condition swim has.
    Swim is currently not in swim's own country (uk) but in Canada on a long trip.
    Swim cannot afford to travel back to UK at present and has about 2 weeks worth left and is desperate. Benzo withdrawal will likely kill swim, gets extremely sick 48 hours without dose.

    So swim is panicking bigtime (which in effect is requiring more clonazepam) and has seen pharmacists with prescription only to be told there's nothing can be done. Swim can not see a doctor as doesn't have the medical card required and can not get one.

    Swim can not afford to run out of this medication and is wondering is it legit to buy from these 'buy online no prescription'n websites, as thinks they look a bit sketchy. If anyone has any experience, especially with Canadian sites please please advise.

    Thank you in advance.
     
  2. checkcall

    checkcall Newbie

    Reputation Points:
    3
    Joined:
    Jul 30, 2010
    Messages:
    8
    It is *possible to potentiate the clonazepam with GFJ, possibly giving it a longer half life and allowing more time between doses. SWIM gets a script for valium and there is infact a sticker right on the bottle saying "Do not eat grapefruit or drink grape fruit juice while taking this medication." SWIM has also heard that this potentiation method works with most popular benzos other than ativan, due to it's different structure and renal metabolism instead of hepatic (liver). SWIM has tried the method before and can say with a fair amount of confidence that it works for valium. Good luck, I know how bad withdrawls can be...
     
  3. neverspeakagain

    neverspeakagain Silver Member

    Reputation Points:
    17
    Joined:
    Feb 10, 2010
    Messages:
    40
    31 y/o
    thanks for your reply
    SWIM has already reduced the dose to every second night because of clonazepam's long half life. SWIM also has a few long acting diazepam 10mg pills left but this is simply for withdrawals. Regardless SWIM is running out real fast and needs clonazepam. SWIM would go for it and buy online, it's almost $XXXUS for 180 pills (same price in each strength). SWIM would get the 2mg ones but it's too much money to risk if it isn't legit.
    SWIM is really panicking and therefore needing to take even more clonazepam.

    neverspeakagain added 3 Minutes and 27 Seconds later...

    So the grapefruit is supposed to give it a longer halflife due to renal metabolization? SWIM will try and research this but SWIM also has renal problems and has to be very careful. Can not consume too much protein etc.
    All problems from diabetes that SWIM has which has also destroyed the nerves in SWIMS GI tract which is why clonazepam was prescribed.
     
    Last edited by a moderator: Aug 21, 2010
  4. imyourlittlebare

    imyourlittlebare Palladium Member

    Reputation Points:
    1,510
    Joined:
    Jun 11, 2007
    Messages:
    983
    start tapering now to try and decrease the risk of wd. My best advice would be to go to an emergency room and explain the situation. Expensive? Probably but better safe than sorry.

    Other option may be to use valerian root, passionflower, l-theanine, and skullcap. All legal, can be purchased at healthfood stores, and could help the situation. Valerian, passionflower, and skullcap.

    Skullcap for sure has minor activity at bz receptor subtypes. Valerian may or may not have any GABA-A activity, l-theanine potentiates the effects of bzs and may be useful for a significant taper or as adjunct to skullcap since it increases GABAergic activity.
    Heres some info on passionflower and kava

    PURPOSE: A tri-substituted benzoflavone moiety (BZF) recently isolated from the methanol extract of aerial parts of the plant Passiflora incarnata Linneaus had exhibited encouraging results in countering the dependence produced by addiction-prone substances like morphine, nicotine, cannabinoids and ethyl alcohol, during the studies performed by the authors. Since the BZF moiety had exhibited significant anxiolytic properties at 10 mg/kg p.o. dose in mice, therefore, it was desirable to evaluate this potential phyto-moiety (BZF) for its own dependence-liabilities It was also deemed viable to evaluate BZF moiety for its possible usefulness in countering the dependence-liabilities associated with the chronic use of benzodiazepines keeping in light their tremendous clinical use in the management of anxiety and insomnia. METHODS. Different groups of mice were administered BZF alone (10, 50 or 100 mg/kg, p.o.), and concomitantly with diazepam (20 mg/kg, p.o.) in a 21-days treatment regimen, followed by no treatments for the next 72-hours. The withdrawal effects in the form of ambulatory behavior of the treated animals were recorded on the 25th day using an Actophotometer. RESULTS. The BZF-alone (three doses) treated mice exhibited a normal ambulatory behavior on 25th day. Mice groups receiving co-treatments, i.e., BZF-diazepam concomitantly, also exhibited a normal ambulatory behavior in a dose-dependant manner, i.e., the higher dose of BZF (100 mg/kg) being more effective in countering the withdrawal effects of chronically administered diazepam than the lower doses (10 or 50 mg/kg). CONCLUSIONS. The studies revealed that the chronic administration of the BZF moiety (three doses), did not exhibit any dependence-liability of its own, even upon an abrupt cessation. Additionally, the BZF co-treatments with diazepam also prevented the incurrence of diazepam-dependence, which might be because of the aromatase enzyme inhibiting properties associated with the BZF moiety.

    [h4]Background[/h4]
    Passion flower (Passiflora incarnata) is used in traditional medicine of Europe and South America to treat anxiety, insomnia and seizure. Recently, it has shown antianxiety and sedative effects in human.
    [h4]Methods[/h4]
    In this study, anticonvulsant effects of hydro- alcoholic extract of Passiflora, Pasipay, were examined by using pentylentetrazole model (PTZ) on mice. Pasipay, diazepam, and normal saline were injected intraperitoneally at the doses 0.4–0.05 mg/kg, 0.5–1 mg/kg and 10 ml/kg respectively 30 minutes before PTZ (90 mg/kg, i.p). The time taken before the onset of clonic convulsions, the duration of colonic convulsions, and the percentage of seizure and mortality protection were recorded. For investigating the mechanism of Pasipay, flumazenil (2 mg/kg, i.p) and naloxone (5 mg/kg, i.p) were also injected 5 minutes before Pasipay.
    [h4]Results[/h4]
    An ED50 value of Pasipay in the PTZ model was 0.23 mg/kg (%95 CL: 0.156, 0.342). Pasipay at the dose of 0.4 mg/kg prolonged the onset time of seizure and decreased the duration of seizures compared to saline group (p < 0.001). At the dose of 0.4 mg/kg, seizure and mortality protection percent were 100%. Flumazenil and naloxone could suppress anticonvulsant effects of Pasipay.
    [h4]Conclusion[/h4]
    It seems that Pasipay could be useful for treatment absence seizure and these effects may be related to effect of it on GABAergic and opioid systems. More studies are needed in order to investigate its exact mechanism.


    Kava doesnt act on BZ receptors. But it has been shown to help those getting off bzs. Heres an article.

    http://www.lycaeum.org/research/researchpdfs/2001_malsch_1.pdf
     
  5. neverspeakagain

    neverspeakagain Silver Member

    Reputation Points:
    17
    Joined:
    Feb 10, 2010
    Messages:
    40
    31 y/o
    That was very helpful, thank you very much.
    SWIM will try these...SWIM has also started tapering but is going to run out regardless and needs clonazepam for SWIMs condition. SWIMs GI tract will go into severe spams and that's not even beginning to speak of withdrawals.
    SWIM also is in trouble here as SWIM had two hospital admissions due to flareups of SWIMs condition totalling $100,000 in medical bills and having troubles with the insurance paying out. So pretty sure everybody will refuse to help SWIM right now as a result of this.
    SWIM just really wants to know if anyone has experience buying online, is it legit?
    Also the sites swim checked say *GENERIC clonazepam and SWIM doesn't really know if this means anything/will have any implications/differences.
    SWIMs prescribed clonazepam has always been 'rivotril'.

    neverspeakagain added 3 Minutes and 28 Seconds later...

    Also SWIM is on 1200mgs gabapentin for the GI problems but SWIMs consultant says clonazepam is also necessary. SWIM really noticed the difference in the muscle spasms when put on clonazepam. They stopped. They start up about 48hours without the prescribed dose. SWIM ran out in Egypt where they could not get clonazepam and prescribed 10mg long acting diazepam tablets, to take 30mg doses. SWIM was in pain but it helped the withdrawal hell.
     
    Last edited: Aug 20, 2010
  6. fizzle

    fizzle Silver Member

    Reputation Points:
    310
    Joined:
    Jul 2, 2006
    Messages:
    570
    Male from USA
    It is possible to obtain clonazepam online but it is very risky and it could take up to a month for the pills to show up, assuming they made it through customs. At the very least you will have to wait 2 weeks. Moreover, extensive research should be done to find the best, most reliable place to buy from. You don't just type in "buy clonazepam" into Google and order from the first site that pops up. The legit sources are very hard to find. Even if you manage to find a legit source, there is no guarantee. Furthermore, the quality of the pills is often times very questionable. It is possible that they may even be harmful or a totally different drug than what you wanted.

    This is coming from Swim who, in the past, would frequently order clonazepam online. It is a very foolish thing to do as he did get 2 notices from customs saying they seized his order. It is illegal and therefor no one can recommend doing it or give out any sources.

    Your friends best bet is to taper off of the clonazepam. He is in a tough position but he should not make it any harder by ordering a scheduled drug online and risk getting into legal trouble, not getting the pills, or getting a harmful drug. Plus, his anxiety will increase 10 fold after he places that order as he waits for weeks checking the mail religiously with his fingers crossed hopping that he doesn't see a customs letter, only to find out his money was taken and nothing was ever shipped out in the first place.
     
  7. checkcall

    checkcall Newbie

    Reputation Points:
    3
    Joined:
    Jul 30, 2010
    Messages:
    8
    Ok, to follow up on my point, the GFJ (white works better than ruby red or the fruit itself) occupies the enzymes in the liver that would normally be used to break down the chemical. So less enzymes available to break down the chemical = more chemical in your blood for longer periods of time. Specifically, GFJ occupies the Cytochrome P450 CYP 3A4. According to wikipedia, this is the enzyme responsible for the breakdown of clonazepam. Thus, theoretically, it should be broken down more slowly and you will get more long lasting results out of a single dose. As I stated earlier, most popular benzos with the EXCEPTION of ativan (since it is metalbolized renally) are affected by GFJ. You may have misinterpreted my orginial post, there is no need to worry if you have kidney issues. Also, SWIMs script for valium has a big sticker "Do not drink with Grapefruit Juice" stuck to the bottle. Kinda amusing for those without a background in psychpharmacology :)

    checkcall added 9 Minutes and 41 Seconds later...

    Oh, and furthermore, what's the risk of attempting to potentiate your dose with some white GFJ? You waste a few bucks on some juice? It's certainly worth a shot.

    Also, I would second fizzle's sentiments: it's just not worth it. There are too many things that could go wrong in the process and it will take weeks to get to you even IF everything else goes according to plan (which is a big IF)....

    Take care of yourself
     
    Last edited: Aug 21, 2010
  8. east_of_eden

    east_of_eden Titanium Member

    Reputation Points:
    683
    Joined:
    May 27, 2009
    Messages:
    614
    For the OP, has swiy thought about looking for needle exchanges or methadone clinics nearby? the reason swim asks is because it can be very easy to get benzos (especially at methadone clinics).

    of course, swim only knows about the US clinics and it may be different in Canada, but this might be a good place to start looking.

    Also, swim isn't sure why swiy wouldn't be able to go to a doctor. even if swiy has no insurance and had to pay cash, wouldn't it be worth it? swim pays cash everytime she gets her scripts.

    or what about calling your regular doctor in the UK? there has to be a way for people to get their prescriptions when in a foreign country.

    good luck.
     
  9. Jatelka

    Jatelka Psychedelic Shepherdess

    Reputation Points:
    5,668
    Joined:
    Oct 16, 2005
    Messages:
    5,479
    I will say, that many of the studies on GFJ and benzodiazepines were done with the "bog-standard" white stuff.

    The "Only ruby GFJ works" thing seems to be a myth
     
  10. neverspeakagain

    neverspeakagain Silver Member

    Reputation Points:
    17
    Joined:
    Feb 10, 2010
    Messages:
    40
    31 y/o
    Yeah swim really doesn't understand how this would work. In swims experience nothing will help withdrawal other than more benzodiazepine.

    Swim honestly, really doesn't think a taper is possible with the little swim has left and has no faith in anything other than the ashton method of a very slow taper with diazepam replacement....which swim can't get either,

    Swim considered having their prescription shipped from the UK but sees no way round customs. Everything (gifts) swim has ever sent/recieved from the US/Canada has been raided by customs.

    But...if something is shipped within the country swim is in, it does not pass customs, right??

    Swim really appreciated all the help and suggestions so far but is really panicking now.
     
  11. DITN

    DITN Newbie

    Reputation Points:
    -10
    Joined:
    Aug 27, 2010
    Messages:
    23
    Yes, SWIY can find Clonazepam and many other benzo's online with no prescription. This cat SWIM knows has ordered 4 times in the past from an oversea pharmacy with no problems and the pills were legit. Much more expensive than having a real doctors prescription and there's always the risk of it getting seized by customs, so it's not without its negatives.

    No discussing specifics though as per the rules. You need great google-fu to find these sites, but they are real.
     
  12. neverspeakagain

    neverspeakagain Silver Member

    Reputation Points:
    17
    Joined:
    Feb 10, 2010
    Messages:
    40
    31 y/o
    SWIM got SWIMs dr in the UK to copy the prescription for customs and SWIMS friend is sending the clonazepam priority mail, swim is such an idiot for not thinking of this in the first place.
     
  13. poppigurl

    poppigurl Newbie

    Reputation Points:
    0
    Joined:
    Dec 31, 2015
    Messages:
    1
    Intro to me, and why I should be allowed to be in your Forum!

    I probably have been "kicked out" of this forum according to an automated email that I just found and need to learn from(?). I'm 48 years old now, but was it human? The message sent I mean. Or was it vegetable, or mineral? I would like to perhaps use my prior (I mean current) knowledge as a recovering human being of 48 years to teach and treat someone who is also needy like me, with compassion! I am an ex-LVN (Licensed Vocational Nurse) of 8 years prior to the well known "burnout" phenomenon who no longer has that invaluable ticket to the work-force. Yes, I'm "on the dole" a sin against humanity according to my upbringing as an adopted only child of a conservative, Lutheran, workaholic, and admittedly good family! But then it (me) grew up! I have a fear of authority and institutions I guess, because I wanted to jump in headfirst and am so impatient, that in my haste, I forgot to read the RULES. I guess rules were never my strong suite, but admittedly are of the utmost import, I admit! They keep us SAFE! So, may I in all sincerity, please join your forum? Forgive my ignorance, but I am going through some life and death medical problems that has a side effect of "confusion", called Atrial Fibrillation, had low K+, and had a Myocardial infarction. I am Bi-Polar (perhaps I should not have told you that, it doesnot mean I'm stupid, or violent)! I am also going through menopause, which is much worse than I thought it'd be. My kindly therapist says hers took 10 years! Ido hate and want to fight against addiction and mental health stigmas! I have 3 children, one 28 and out, and 2 teens at home, plus a new additional teen roomer! To add to my stress, even though I no longer have a career, my spouse has had Type 1 Diabetes since before our 18 years together, and to top THAT off he has extreme lower back pain from a ruptured disk, for which against my advice, well trained wonderful surgeons did an "experimental procedure" and messed with his back, or actually his nervous system (i.e.-brain/spine/nerve bundles, all branching off the spinal column, and all of this equals our very delicate human nervous system)! I then acquiesced that indeed he MUST have been in a lot of PAIN! No more hypochondriac jokes! After his surgery, we found a pain specialist in San Francisco, who gave him what he needed (Oxycontin and time released MS Contin). BUT, now they are taking it away, after oh, about 10 years I'd say! This is CRUEL and INHUMANE treatment! It's a good thing I was knowledgeable about this stuff! Every time the Dr.s attempt to help us disabled people with our pain as they are trained to do, the DEA is breathing down their neck! Whether it be plain ol' "mary jane" for appetite or pain, or massive doses of opioids for pain, or benzodiazepines for anxiety and seizure activity, or to prevent alcoholism withdrawal whichcan result in death without it! As an ex-nurse, I've experienced things, even though I'm a bit confused at times, Dr.'s/MD's are basically verygood (though also human), and so am I! They TRY to help people! But, they constantly come up against the most ridiculous barriers, as if a cop knows about pharmacology! Last I checked, they still group all illicit drugs into one category and call them "Narcotics"! An educated person (or even just curious) would know "narc" means (in greek or Roman)to sleep! This would cover Opiates, and Benzos and sleeping aids. Not hallucinogens, or methamphetamines, or cocaine! What I'd like people to know, is all of these drugs are different! Alcohol is a drug! Testosterone (the kind males naturally excrete from gonads and other glands at puberty, are drugs! Well, chemicals actually, while naturally occurring, act as a drug and a strong one at that! Ask a transexual!
    See, I was hospitalized a few days ago, and still am on the mend (I hope)! So, I pray that you'll give me another chance to read over those rules, and figure out just how I broke them. I hope it wasn't the avatar of Kafka portrait by R. Crumb!? They are 2 favorites of mine. Or my user ID, which I can change (the ID that is!) Sorry I over did he length of the writing it's just practice,:eek:
    By the way I'm from "Cali"!~ aka- Ms. Lisa Davis
     
  14. Eden

    Eden Titanium Member

    Reputation Points:
    213
    Joined:
    Dec 4, 2007
    Messages:
    123
    Hello poppigurl, Sorry to hear of your troubles. As a sentient human being I empathize. You sound like a very interesting person and I'm sure you have much to offer. The more colorful the better imo. Some advice if I may?

    1.Please post this appeal in the appropriate section as this is a seven year old thread about someone who needed medical advice specific to their situation.

    2. Please read the rules about self incrimination and how to avoid it.

    3.When replying within an established thread, please attempt to stay on topic as much as possible so that the op(original poster) receives adequate responses/assistance etc. to their question or situation.

    4.This is a wonderful place to get information and help that honestly can be extremely difficult to find anywhere else. Please do yourself a favor and maybe just take some time to acquaint yourself with all the rules of the forum and when you are ready, perhaps post an introductory thread about yourself so you have a chance to tell your story etc.

    Good luck, be well.
    Eden