Codeine question?

Discussion in 'Codeine' started by bob78, Oct 14, 2006.

  1. bob78

    bob78 Silver Member

    Reputation Points:
    21
    Messages:
    25
    Joined:
    Sep 6, 2006
    I take morphine in 20mg tablet form but prefers Codeine instead.
    He used to take codeine phosphate but it got changed to morphine a couple of months ago. Swim thought that the morphine would be better but after taking some of his old codeine tablets I think the codeine gives better pain relief as well as giving a better buzz.
    Maybe it's the poor bioavailability of taking morphine orally?
    I would like to know the difference between Dyhydrocodeine and Codeine Phosphate before asking the G.P for advice.
     
    Last edited: Oct 14, 2006
  2. ningbar

    ningbar Newbie

    Reputation Points:
    5
    Messages:
    12
    Joined:
    Mar 10, 2006
    from U.K.
    I have been prescribed codeine for a real medical condition for several years

    at one point he thought it would be fun to get "stronger" opiates on prescription and also not to have to do CWE all the time

    alas he found both dihydrocodeine and morphine to be far less effective, even in very large ammounts

    i think its very much down to individual metabolisms, but I went back to the codeine through his own choice and has learnt to enjoy what he has instead of trying to get stronger meds

    cheers
    Ningbar
     
  3. Forthesevenlakes

    Forthesevenlakes Platinum Member

    Reputation Points:
    1,408
    Messages:
    1,974
    Joined:
    Feb 26, 2006
    Dihydrocodeine is simply about twice the strength of codeine, and thats the only difference SWIM can really think of.

    Codeine is very bioavailable, much more so than morphine. Morphine orally might only be about 10% bioavailable, max. So for a 30 mg pill You would only get 3 mg of that to his brain. This could be why You finds codeine more effective!
     
  4. Nature Boy

    Nature Boy Gold Member

    Reputation Points:
    1,984
    Messages:
    3,878
    Joined:
    May 10, 2005
    from ireland
    ^^^

    True that.

    Although morphine is a more powerful opiate than codeine, orally it doesn't have a very strong effect. It seems to be designed for IV use.
     
  5. bob78

    bob78 Silver Member

    Reputation Points:
    21
    Messages:
    25
    Joined:
    Sep 6, 2006
    Cheers guys, I think he will stay on his slow release morphine 30mg MST as it does help, but will ask his Doctor if he can go back on codeine phosphate 60mg for breakthrough pain instead of quick release morphine 20mg Sevredol. Or do you think I should ask to try Dyhydrocodeine instead?
    It's strange but a few months ago if you told swim he would be turning down morphine in favour of codeine I would of not of believed it.
     
  6. Forthesevenlakes

    Forthesevenlakes Platinum Member

    Reputation Points:
    1,408
    Messages:
    1,974
    Joined:
    Feb 26, 2006
    Dihydrocodeine should be very similar to codeine, just twice the strength. However, SWIM's not sure the bioavailability is as good as regular codeine. For whatever reason, codeine is very bioavailable orally. The 60 mg codeine phosphate may not be a bad idea. It would absorb better than the morphine Sevredol, for sure. I dont hear of DHC being prescribed too often for breakthrough pain, maybe discuss with you's doctor if he thinks itd be a better option.
     
  7. mickenator

    mickenator Titanium Member

    Reputation Points:
    244
    Messages:
    306
    Joined:
    Oct 7, 2006
    46 y/o from U.K.
    If it's mainly for relieving pain then swim prefers there dihydrocodeine and has tried others but eventually came back to these. Serious pain sucks !!! Also the buzz 'aint bad either, but haven't tried doing cwe yet.