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Cold water extraction of Codeiene cough syrup

Discussion in 'Codeine' started by GForce, Feb 12, 2007.

  1. GForce

    GForce Gold Member

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    I was wondering if the same basic principles of cold water extraction would hold true for Robitussin AC. I have recently been prescribed a bottle of this, of which the contents are Codeine phosphate and guaifenisin. Will the guaifenisin form crystaline structures when chilled? SWIM's basic idea was to take the cough syrup, chill it in an ice bath for 5-10 minutes, and then pour the syrup through a coffee filter in order to separate the guaf, assuming it crystalizes. Would this work?
     
  2. Forthesevenlakes

    Forthesevenlakes Platinum Member

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    Guaifenisin is highly soluble in water, so I don't think this would work. Most likely the drugs in there would lower the freezing point of the solution, but they'd stay in solution rather than crystallize out. Perhaps an A/B extraction would work, but I am not sure. If codeine has similar chemical properties to dextromethorphan (and it might, I amn't sure) then the agent lemon DXM extraction MIGHT work. I have to leave right now and can't check on this, but its something to think about, and maybe a member more knowledgable in chemistry than I could say whether or not this extraction would be a viable option.