I hope somebody can answer this. The first time I tried mescaline (500 mg encased in a sugar capsule) as the first wave was coming on I felt nausea and promptly vomited, aside from this the trip was very enjoyable. My stomach contents were 1 drink (3.5 ounces of Jack Daniels and 4 ounces of Pepsi). Prior to popping the pill I had smoked a joint with my friend. Could anything I had done attribute to the nausea/vomiting? If so should I do anything different next time? Also, would it be advisable to take some GRAVOL or something?