Let's start off with 2c-e.. Swim personally loves the chemical, It's just great all around but I am a little burnt out on it and it seems as though everytime I do it the physical struggle to literally live gets harder and harder. Recently, after snorting 20mgs or so it became very unpleasantly hard to breathe and swims pulse was ungodly high and it actually started off spiraling swim into a worried and unpleasant trip due to the fact that while on 2c-e its not fun to be worried about the slightest discomfort because 2c-e tends to magnify things to say the least. As swims heart rate went down the trip became very pleasant and enjoyable. It got swim thinking a little, maybe we had all been overdoing it a little by using 2c-e in high snorted doses at least once a weekend if not twice and maybe once during the week, as I noticed a negative tolerance being built up such as the breathing problem, which generally didnt occurr to that magnitude.. it was litereally everything you could do to focus on taking in every single breath as deeply as possible and it actually began to wear you out.. Now I am finding t21 to be more at ease and enjoyable but I am still researching it to see what negative threats it poses.. but damn the 2c-e trip is an awesome and defying trip on all levels. I am still looking for that perfect chem but for a while he thought he had found it. Maybe RC's are just too hard on ones body after too much over use.