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Effects - Dilaudid VS Codeine

Discussion in 'Opiates & Opioids' started by AnrBjotk, Jun 4, 2010.

  1. AnrBjotk

    AnrBjotk Mercury Member

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    What is the main difference? And what makes dilaudid stronger? Further more, will a large amount of codeine beat a tiny amount of dilaudid?
     
    Last edited: Jun 5, 2010
  2. TarBaby

    TarBaby

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    Dude that like saying who would win in a fight Mike Tyson or Pee Wee Herman.
     
  3. 420Shark210SanAnto

    420Shark210SanAnto

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    well you never know, give Pee Wee a bunch of meth and i'd pay money to see that.

    But thats like compairing heroin to opium. They make H for a reason, it's stronger. Same reason why they make Diluadid, because sometimes codeine doesn't cut it. And it's not so much a matter of opinion, hydromorphone is alot more active than codeine and that's your final answer really...
     
  4. RhinestoneCowboy

    RhinestoneCowboy Titanium Member

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    to attempt to break it down:

    1) codeine VS morphine - morphine is stronger because of its chemical structure, and activity at opiod receptors.

    now, reflux the product with a platinum catalyst, thus hydrogenating it to receive hydrocodone (vicodin) and hydromorphone (dilaudid); both products become greatly stronger once hydrogenated...

    2) vicodin VS dilaudid - once again, nothing has changed besides both products being stronger than their original form. the morphine based chemical (hydromorphone) remains stronger because of its chemical structure, and activity at opiod receptors. even though the codeine got a boost from hydrogenation. The hydrocodone is stronger than its original form.

    that being said, in theory, a massive dose of codeine could be more effective than a small amount of hydromorphone. it's important to remember that the two chemicals are different drugs. even though both are in the same class of drugs (opiods), they act differently at the receptor, resulting in differing effects.

    this also depends on bioavailability and route of administration. hydromorphone has low oral bioavailability. hopefully swiyou isn't considering attempting to match or "beat" a hydromorphone experience via codeine intake. That would be a dangerous idea.