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Do pills (OC, Opana, etc..) lose potency overnight in water?

Discussion in 'Oxymorphone' started by Bleeding_Me, Mar 8, 2010.

  1. Bleeding_Me

    Bleeding_Me Silver Member

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    Hey all. Unfortunately SWIM has gotten back into opiates after attending a local Detox program. Tonight, he managed to find 10mg Opana IRs (or "Pinks", around here) and he has a question. If he prepares them tonight, crushes them, spoons them, slightly cooks them, a little cotton and BAM!, up into the syringe, will it lose it's potency overnight? SWIM doesn't want to wake up in the morning and have it not work due to some stupid bullshit... such as losing the active ingredient for being in the water for so long. It may be lazy, but he's been back at it for about a over a week now and back come the withdrawals. This means the last thing he wants is to go through that process all cold and shaky. Does SWIY have any facts or personal experiences which lead to an answer of SWIMs question?? SWIM thanks SWIY for the help!
     
  2. mbarnes0

    mbarnes0 Silver Member

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    Not sure about losing potency but that sure is a nice way to increase the risk of a 'dirty shot'. Leaving it like that can be enough time for bacteria to colonize inside the syringe.
     
  3. vellocet

    vellocet

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    An older xanax addict swim used to know years ago, who died from her addiction, swore that pills lost potency after they weren't as fresh. This was a lady who would start to freak out if she had 60 xanax left. Swim thinks her tolerance may have helped her determine the strength. Different chemical, but still interesting.

    Not to be your mother, but Swiy shouldn't inject pills. If he must, he should use a wheel filter. Don't heat up the pill, opiates are water soluble and cooking it will make more nonopiates dissolve in the water that may resolidify in the syringe. Crush it up and let it sit in the water for a good while. As was stated earlyr, Swiy shouldn't let stuff sit out over night, and please use bottled water instead of tap. Tap water can result in some Nasty infections.
     
  4. mbarnes0

    mbarnes0 Silver Member

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    Did she mean that they would seem to lose potency relative to when the pills were acquired/script filled?

    SWIM would say that substances can lose potency over time or even expire. He doubts that ~12 hours would have much of an effect on potency, whether dissolved in water or not. He could be wrong on that though.

    Aside from the possibility of bacteria, SWIM has noticed that after leaving a preloaded rig with an oxycodone solution sit for an hour or so, some settling or re-precipitation occurring inside the barrel. SWIM thought he had filtered the solution well but had only used cotton, not a micron filter.
    The settling or re-precipitation of solids illustrates some of the danger involved with injecting pills. Pills should not be injected as they weren't made for that route of administration, but if it is going to happen a wise investment would be in some micron filters.
     
  5. Helene

    Helene Gold Member

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    If you're living in a developed country, such as the UK or the US, this isn't actually the case. For use as a liquid for dissolving drugs for injection, tap water is almost always better than bottled water because the bacteria count will be lower. The bacteria count in bottled water is much higher than in tap water, and varies according to the temperature at which it is stored, and can be very high if someone has drunk water from the bottle.

    This is not to say that the bacteria in bottled water are harmful if drunk – the acid in your stomach is perfectly well able to kill bacteria at these levels, however when injected intravenously, they can cause infections.

    This information is from a great resource on the Exchange Supplies website, an interactive poster that details all the risks associated with injecting using different sources of water. It can be found by clicking this link here - http://www.exchangesupplies.org/dru...es_water_risks_poster/water_risks_poster.html
    Their list reads as follows (from lowest risk to highest risk):

    Unopened ampoule of sterile water for injection
    Viral Infection: No risk (unless shared)
    Bacterial Infection: No risk

    Water boiled in a kettle then cooled
    Viral Infection: No risk (unless shared)
    Bacterial Infection: Very low risk

    Cold water freshly run from the kitchen tap
    Viral Infection: No risk (unless shared)
    Bacterial Infection: Low risk

    Bottled water
    Viral Infection: No risk (unless shared)
    Bacterial Infection: Medium to high risk

    Hot water from a tap
    Viral Infection: No risk (unless shared)
    Bacterial Infection: Medium to high risk

    Toilet water
    Viral Infection: No risk (unless shared)
    Bacterial Infection: High risk

    Puddle water
    Viral Infection: No risk (unless shared)
    Bacterial Infection: High risk

    Part-used ampoule of water for injection
    Viral Infection: High risk
    Bacterial Infection: High risk

    Shared cup of water
    Viral Infection: High risk
    Bacterial infection: High risk

    Do check out the link, it contains loads of great harm reduction advice. It also gives a whole wealth of information about each different water source (such as the fact that tap water is almost always better to use for injecting than bottled water), and explains the risks of using each one. Plus tips are given on how to make water safer for injecting.

    H
     
  6. HATEu4NOW

    HATEu4NOW

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    Opana ER Only

    The actually gain potency as the water will first gel up the pill, but if SWIY lets it sit stiring on occasion this will help break down the plolycaharide matrix holding the oxymorphone.

    SWIM suggest to place it in the highest proff alcohol SWIY has for at least 1 hr stiring every 15min then ingest to make at least 25% more potent. Drink a beer with it or better wet 2 more shots. The alcohol should be wearing off just as the oxymorphone is kicking in. The longer they soak the better, let em sit for days or weeks stiring twice daily and they will keep getting stronger and stronger baby! If you are going the alcohol route dont add water, this will make it take longer, use 90%+ isoproply alcohol (rubbing alcohol). Everclear is the best for this process. Alcohol is used because it doesn't cause the polysacharide matrix to gel up causing the process to take longer. :(
     
    Last edited by a moderator: Dec 23, 2011