1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.
    PLEASE HELP

Combinations - DXM + Hydrocodone with APAP (+ Salvia)

Discussion in 'DXM' started by DxCore, Mar 12, 2006.

  1. DxCore

    DxCore Newbie

    Reputation Points:
    35
    Messages:
    51
    Joined:
    Feb 8, 2006
    Has anyone tryed this combo? maybe a low dose of each just was wondering..i just took some Vikodin for back pain so thats where my question came from if i were to try and trip right now on some dex..


    DxCore.

    Safe trippin (<
     
  2. Fantasian

    Fantasian Silver Member

    Reputation Points:
    1,024
    Messages:
    1,150
    Joined:
    Sep 28, 2005
    30 y/o from U.K.
    i were to try and trip right now on some dex..
    - Careful on Self incrimination

    In answer to your question DXM is suppose to potentiate Hydrocodones effects therefore expect heavier sedation and a greater degree of euphoria as well as the other usual effects accociated with DXM. Might be worth noting however that drug synergies are only for experienced users and this combination can significantly increase the effects of both drugs. Start low if this is you's first time with the combo.
     
  3. Muirner

    Muirner Gold Member

    Reputation Points:
    38
    Messages:
    984
    Joined:
    Feb 19, 2005
    from U.K.
    Maybe you can give it a whirl, but still there are a few things i'll caution you of first. If your going to go ahead and do this, i would hope that you have taken vicoden before and you know how you'll react. If this is true then you should know when your tripping you will feel everything but 10x more intense. SO if your going to do this, i'd advise to start with 1/4th of a pill, maybe 2mg of hydrocodine (that's the active in vicoden if i remember right)... Remember you can always take more, but never less, and explaining to a doc what happend sucks more then playing it safe.
    (<

    Muirner
     
  4. RoboCop

    RoboCop Platinum Member & Advisor

    Reputation Points:
    313
    Messages:
    881
    Joined:
    Jan 22, 2004
    from earth
    What exactly are you all trying to accomplish? Seems to me like you are trying to push your limits until your heart stops beating.

    I have liked both substances seperately but would never combine.
     
  5. DxCore

    DxCore Newbie

    Reputation Points:
    35
    Messages:
    51
    Joined:
    Feb 8, 2006
    No No heh, SWIM never did try it I was just wondering if anyone has tryed it or what not.. I was perscribed Vikodin for back pain and was wondering if its possible to trip while on it.
     
  6. Nagognog2

    Nagognog2 Newbie

    Reputation Points:
    1,936
    Messages:
    7,163
    Joined:
    Feb 1, 2005
    DXM in combination with opiates are currently being researched in the medical community. It seems that a VERY small dosage of DXM has the effect of preventing tolerance to opiates from developing. At least that's the idea. How this works, and what sort of potentiation is at play here is a big, fat unknown. Your monkey is advised to be very, very careful here. It's called research because no one knows all the answers.
     
  7. static_vodka_420

    static_vodka_420 Silver Member

    Reputation Points:
    130
    Messages:
    209
    Joined:
    Jul 25, 2007
    from U.S.A.
    Re: HydroCodone+DXM

    I am assuming You has experience with both substances allready

    I have been known to use this combo when his supply of opiates were running low

    his usual dosage was around 300mg dxm followed a few hours later by 30mg hydrocodone inuffulated

    the dxm potentiated the opiate euphoria and nod while the hyrocodone brought back the numbness and dissacociation of the dxm

    it was a rather relaxing combo in swims opinion but is most likelly unsafe so unless experienced is not safe..maybe not even then
     
  8. Genith

    Genith Newbie

    Reputation Points:
    0
    Messages:
    3
    Joined:
    Nov 10, 2008
    40 y/o from U.S.A.
    Hydrocodone with APAP + DXM + Salvia

    711 mgs of dex and 3 10/500 lortab plus some salvia.

    How safe would this be?
     
    Last edited by a moderator: Jun 3, 2009
  9. Sushi

    Sushi Signals From 93 Dimensions Gold Member Donating Member

    Reputation Points:
    1,604
    Messages:
    368
    Joined:
    Jan 25, 2009
    45 y/o from Łódź
    Re: Lortab+dxm+salvia

    This is international forum, so please use international names of substances. It's Hydrocodone in this case. And state the exact dose - what is "3 10/500"? And state You weight too. And use the search engine. Here's a thread devoted specifically to DXM+Hydrocodone, finding it took about 10 seconds:
    https://drugs-forum.com/forum/showthread.php?t=16800&
    But there are more of them of course. And You can always type "opiates" and "opioids" into search, it will give You even more results.

    Salvia divinorum is the same case - there are threads devoted to mixing DXM with Salvia, here and at Salvia sub-forum too. Just use the search engine.

    Madlab is not a practitioner but it looks like a dangerous mix to her. Physically dangerous in case of combining big dose of DXM with an opioid (what's the exact dose of Hydrocodone in miligrams You is going to ingest? and what is You weight?). And potentially very overwhelming mentally in case of Salvia.
    To answer You question, ingesting any psychoactive can't be called safe. Let alone mixing various psychoactives. And mix like this is most certainly risky. But she is not going to assess decisively just how risky it would be, although she suspects it can even be life-threatening due to respiratory depression. Please correct her if she's wrong, but combining DXM with opiates results in synergy, and in case of 711mg of DXM mixed with Hydrocodone one should expect a powerful and dangerous reaction.
    Did You try all three components of this mix before?
     
  10. Genith

    Genith Newbie

    Reputation Points:
    0
    Messages:
    3
    Joined:
    Nov 10, 2008
    40 y/o from U.S.A.
    Re: Lortab+dxm+salvia

    Weight 180
    30mg hydrocorone / 1500 apap... may use a cwe

    Genith added 16 Minutes and 7 Seconds later...

    I decided to leave the hydrocodone out
     
    Last edited by a moderator: Jun 10, 2009
  11. 123546789

    123546789 Newbie

    Reputation Points:
    0
    Messages:
    16
    Joined:
    Aug 17, 2008
    Re: Lortab+dxm+salvia

    Combining DXM and hydrocodone could be lethal due to combined respiratory depression. However, mixing salvia + DXM is relatively safe.
     
  12. CoryInJapan

    CoryInJapan Silver Member

    Reputation Points:
    76
    Messages:
    370
    Joined:
    Jan 21, 2009
    from U.S.A.
    Re: Lortab+dxm+salvia

    But DXM is a semisynthetic opioid , So would that make it less dangerous?

    CoryInJapan added 0 Minutes and 42 Seconds later...

    Dangerous to mix with another opiod
     
    Last edited: May 10, 2009
  13. helikophis

    helikophis Newbie

    Reputation Points:
    1,071
    Messages:
    323
    Joined:
    Oct 28, 2008
    35 y/o from New York, U.S.A.
    Re: Lortab+dxm+salvia

    Although DXM is an enantiomer (structural mirror) of an opioid, it is functionally quite different. Characterizing it as an opioid isn't really very accurate; in terms of its pharmacokinetics, safety profile, or subjective effects, it is a completely different substance. Although there is some overlap in effect, it is achieved by different mechanisms. There is a lot of individual variation with DXM: can be a relatively safe drug, but it can also be a relatively harmful one.

    The dose of hydrocodone the OP discussed was not an especially high one, although the DXM dose was moderately high. While the combination shouldn't be extremely dangerous, it is probably not advisable to mix opiates in any quantity with DXM. Certainly doses higher than the ones discussed are right out. DXM does produce respiratory depression, and so combination with other drugs with similar effects, including opiate analgesics and alcohol, should be avoided, because of the potential for synergy between them.

    Hope that helps.
     
  14. Euthanatos93420

    Euthanatos93420 Silver Member

    Reputation Points:
    649
    Messages:
    1,249
    Joined:
    Mar 22, 2007
    from U.S.A.
    Re: Lortab+dxm+salvia

    That's probably the absolute maximum one wouldnt wnat to combine any opiate with. If You is potentiating with WGFJ remember that BOTH will be (Moreor less) potentiated.

    Which would be complicated because they're all processed by the same liver enzyme. One might want to experiement with lower doseages of DXM to assay level of potentiation and get an idea of what might happen at the levels You mentions originally.

    DXM+Salvia is a fine combo. No problems there. I would recommend Marijuana assuming You has no problems with it alone. Other things might be 5-HTP. A personal favorite potentiator for Swim. Though one must be advised that Anything that affects seratonin levels in combination with DXM might put one at risk for Seratonin Syndrome.