From MS Contin to Codeine

Discussion in 'Codeine' started by beena, Mar 23, 2007.

  1. beena

    beena Palladium Member

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    Mar 14, 2007
    39 y/o from U.K.
    I have been taking large quantities of MS Contin (between 350mg -650mg per day) and has built up a tolerance. If I was to take codeine how much would You recommend I takes? I have not used codeine before.
  2. Tortoise

    Tortoise Silver Member

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    Jan 19, 2007
    from Australia
    I believe that with the phenomenal tolerance you have obviously built up, there is no safe level of codeine that you could take to give you any significant pain relief or subjective effects. The ceiling dose for codeine is around 400 to 500mg. After this, the liver cannot convert any more to morphine (which is obviously active, whereas codeine isn't) regardless of tolerance. Taking more is useless and dangerous.

    400mg of codeine is roughly equivalent to 40mg of morphine depending on your metabolism, so I don't think you'll get much use out of codeine at all, sorry to say!