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Side effects - Guaifenesin harmful effects

Discussion in 'DXM' started by Neurocity, Jan 9, 2010.

  1. Neurocity

    Neurocity Silver Member

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    Hello, I'm new here but haven't been able to find anything on this topic with the search bar. A friend of mine is interested in dxm but only has extra-strength Mucinex DM on hand--1200 mg guaifenesin and 60 mg dextromethorphan. Anyway, he knows that guaifenesin should be avoided but is too damn lazy to go hunting for some dxm only medicines, so he wanted me to ask how far he can push the guaifenesin before it becomes a problem.

    So I guess what he wants to know is how much it usually takes to make you vomit. (If it changes anything, the tablets are extended release. And yes, I know, him and I are probably dumb for not knowing this.)
     
  2. staples

    staples Gold Member

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    Re: Dumb question, but how far should you go with guaifenesin?

    Guaifenesin isn't very toxic. I believe that formulation (Mucinex DM) uses a controlled release to administer 600mg of Guaifenesin twice throughout the day.

    Everyone is different so it's not very easy to predict how much Guaifenesin would cause your friend to vomit. However, I would be surprised if your friend vomits from up to 4 times that dosage (3600mg total in one day). Whether or not he does, though, I don't think that dosage is very good for anyone's body; it could cause kidney stones.

    It's not hard to find a formulation which only contains dextromethorphan...
     
  3. TheMainException

    TheMainException Silver Member

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    Re: Dumb question, but how far should you go with guaifenesin?

    Do the work and find DXM only...it's worth it. Once SWIY finds a good brand of DXM only, SWIY can be happy knowing that the likely hood of vomiting is highly decreased since DXM alone can often cause vomiting at high doses.
     
  4. Rin_Weh

    Rin_Weh Silver Member

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    Re: Dumb question, but how far should you go with guaifenesin?

    It's not the vommiting, if it occurs, that's the bad part.
    It's the feeling of ones stomach being twisted violently like a pulsating sphere of red.
    Puking would be a relief. Sometimes puking doesn't happen.
    Not good to ingest a lot of this stuff.
    Really....take the time and look for something with dextromethorphan only if one must use DXM.
     
  5. supervalu

    supervalu Newbie

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    Re: Dumb question, but how far should you go with guaifenesin?

    Last week, SWIM wanted to try DXM desperately and she took 15 generic Mucinex D tablets for a total of 6000mg guaifenesin and 300mg DXM. SWIM took a few Pepto-bismol tablets and some Tums in hopes of counteracting any nausea she might experience. SWIM has an extremely strong stomach and very rarely vomits.

    Baaaad decision. SWIM vomited explosively and then had a seizure (probably unrelated to the guaifenesin, but worth noting anyway). She ended up in the ER for 2 days.

    This stuff is serious. It is designed to assist the body in expelling! The trouble is that there is no telling how much will make your friend vomit until your friend actually tries it.

    SWIM truly thought she would be able to suppress whatever nausea came up, but she was very, very mistaken. :cry:

    Tell your friend to find a DXM-only product. It's worth it.
     
  6. lightning_po

    lightning_po Silver Member

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    Re: Dumb question, but how far should you go with guaifenesin?

    My pet fox once supplemented 120mg of DXM to 1,200mg of guaifenesin (10mg DXM 100mg guaifenesin per 5ml) after drinking a bottle of DXM only syrup (118ml of 15mg dxm per 5ml syrup = 354mg). My fox had a mostly normal trip without an upset stomach but actually coughed a little bit during the trip, which freaked my pet fox out for a second. Based on how my fox reacted to the guaifenesin, I would NOT reccomend more than say 1,800mg max.
    The only thing I ACTUALLY reccomend, based on my pet fox's experiences is to buy the syrup with only DXM ingredients. Drug companies reccomend no more than 1,200mg of guaifenesin every 4-6 hours, however.

    Final Reccomendation : My pet fox told me telekenetically to tell SWIY to just drink the nasty DXM only syrup or extract from syrup and capsulize...
     
  7. dyingtomorrow

    dyingtomorrow Palladium Member R.I.P.

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    Re: Dumb question, but how far should you go with guaifenesin?

    Two days ago SWIM ended up incidentally ingesting 2,000 mg of guaifenesin between syrup and pills (gf bought the shit ones). He tripped fine and didn't get sick at all.

    SWIM just ate about 4,000 mgs of it a couple hours ago (only had the BS pills this time) and doesn't feel sick at all. But he also ate a small bowl of ramen noodles which has muted the DXM effects some, but possibly also made the G-shit not fuck his stomach up.

    Edit: Okay lets make that 6,000 mgs and still okay.
     
    Last edited: Feb 6, 2010
  8. zorgin

    zorgin Newbie

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    Re: Dumb question, but how far should you go with guaifenesin?

    Ahhh...mucinex, packed with more guaifenesin than other preps...but also more DXM, making it tempting.

    I have heard reports from others who have dared to venture into using mucinex recreationally, and the general verdict was 'not worth it'. The nausea never ended, and the experience in general was described as unbearable.

    I have also heard that one might be risking kidney stones with such an excessive dose of guaif, but I don't have medical references to prove or disprove that.

    IF your friend was determined to trip with mucinex, I would suggest not taking it past 5 pills/300mg DXM (and 6g of guaif). It would certainly be more uncomfortable than a DXM only trip.
     
  9. dyingtomorrow

    dyingtomorrow Palladium Member R.I.P.

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    Re: Dumb question, but how far should you go with guaifenesin?

    SWIM's been taking 6000 - 8000 mgs of guaif each time with his DXM 3-4 times a week for the past 3 weeks. (yeah yeah the pure DXM is better, gotta make due with what you have though right?)

    He hasn't experienced any nausea or perceivable unpleasantness from it. Not saying that will hold true for everyone - just SWIM's experience.
     
  10. gonegrowin

    gonegrowin Newbie

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    Re: Dumb question, but how far should you go with guaifenesin?

    SWIM has not been bothered by guaf ever. Except one occasion which resulted in projectile vomiting. SWIM has concluded this one time could be attributed to some other variable than the guaf.
     
  11. Medicator

    Medicator Newbie

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    Re: Dumb question, but how far should you go with guaifenesin?

    swim wanted to know if guaifenesin could b dissolved in water out of mucinex tabs. Swim read some were that guifenesin was highly soluble in water and dxm was not so much.. any ideas??
     
  12. qcksilver89

    qcksilver89 Newbie

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    Re: Dumb question, but how far should you go with guaifenesin?

    my friend called the poison control center about this b/c there was a situation that arose one evening while @ a party- this kid apparently was freakin out and his friend asked someone to call- turns out, according to that organization, there's no fatal dose of guaifenasin... so have fun till you start puking
     
  13. Medicator

    Medicator Newbie

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    Re: Dumb question, but how far should you go with guaifenesin?

    any ideas on my question?
     
  14. _TJM_

    _TJM_ Newbie

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    SWIM had been looking around for a while. For nothing special, for reasons of who knows. SWIM found a bottle, of Robitussin DM Max. SWIM knows, when choosing quality Robitussin its best to avoid anything other than Dextromethorphan. SWIM is horribly wrecked currently mental and physical. SWIM is holding this bottle in his hands, probably will ingest it disregarding all the information he knows. Even tho, SWIMS first robotrip, he ingested well over 2,280MG of Guaifenesin, he came out okay only bad thing that happened was that he vomited three times. What is the exact possibility SWIM will explore anything worse than just throwing up? Has SWIY ever took the risk and ingested a 4 OZ bottle containing Guaifenesin?

    Active Ingredients (in each 5 mL tsp)
    Dextromethorphan HBr, USP 10 MG
    Guaifenesin, USP 200mg​
     
  15. supervalu

    supervalu Newbie

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    SWIM ingested less Guaifenesin than that and vomited so violently that she had a seizure. So, SWIY would have to be an idiot to try that knowing what it could do.
     
  16. _TJM_

    _TJM_ Newbie

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    Guaifenesin Helps loosen up mucus in the chest and throat in order to help somebody who takes it to cough. In really high doses somebody who ingested large quantities of Guaifenesin will feel nauseous even after puking. AFOAF used Guaifenesin containing cough syrup three times in a row when nothing was available. AFOAF did not feel any harmful effects from 4,000MG+ but he is very tolerant of stuff like this.

    P.S
    Swim is very displeased with the negetive rep given on a post above. Sometimes somebody might stumble upon this forum while intoxicated and think its something that its not. Such rube behavior should not be tolerated even in a negative rep post. Prick.
     
  17. qcksilver89

    qcksilver89 Newbie

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    Health officials associated with poison control centers can confirm that taking massive amounts of guafenisen has little to no harmful effects on a person. ... Another thing is i noticed the quote about "being mentally and physically wrecked" but refusing to hold off on tripping. That is foolish and unsafe in my honest opinion. Do your research and know your body- always stay safe!
     
  18. _TJM_

    _TJM_ Newbie

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    So people have seizures from vomiting now eh?

    Guafenisen Is just something to avoid. Just because it causes nausea, vomiting, diarrhea, abdominal pain, or drowsiness doesn't mean its still okay to take every now and than. If somebody is in a store and buys a bottle that has Guifenisen, why wouldn't that person just reach over to the left or right a little bit to get proper cough syrup? Guafenisen is not necessarily horribly harmful or toxic but who wants to have a 99% chance of throwing up on a robotrip?
     
  19. undeadroguelol

    undeadroguelol Newbie

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    Its all about how your body reacts,

    swim has taken roughly 10,000 mg of Guaifenesin and didnt even have an upset stomach.

    however during the same experience with the same medicine that contained Guaifenesin, swim's friend took roughly 3000 mg of Guaifenesin and vomited/dry heaved+intensely sweated for about half an hour but was fine after that

    there is really no way for you to know if its going to be pushing it unless you try it.
     
  20. dala

    dala Silver Member

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    I assume that pure dxm is not available in the U.S unlike U.K where there is several sourses for the pure stuff.
    Is there a law stopping the sale of pure DXM there? or is it possible to U.S citizens to buy from uk websites.
    The prices are reasonable and its clean way to take it, no worrys with fillers and binders, syrups etc or other drugs a al Guaifenesin.