The only opiate I had taken before was Codeine. I started off small, no effects, kept increasing the dosage to no avail. Finally, I felt only slight relaxation at 450mg. I didnt go any further as Ive read you can overdose. So recently I was prescribed Hydrocodone (10/660), Tramadol (50mg)and I also got ahold of some 40mg Oxycontins. I guess Tramadol is a synthetic analog of codeine. I took 6 50mg pills and only got some trouble urinating and some itching. Next I tried the Hydros. First time I only took one, nothing. Two days later I took 2, still nothing. So finally I took 4 and chewed them all up. It got rid of a little pain in my back but that was about it. So I thought for sure that the Oxycontins would do the trick. So I scrapped the coating off, cut the pill in half, chewed up one half and waited, and waited, and waited. After two hours I only felt slightly relaxed so I took the other 20mg. Still however I only felt slight relaxation. So do I just have a high tolerance for opiates? I didnt do all this in the same time period, I split it up every few days or so. Any suggestions on how to maybe make them more potent? The only one of the Oxys, hydros, and tramadols that have anything else in them are the hdros with the Acetaminophen, which I believe your allowed a max of 4g a day. So any suggestions?