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Pharmacology - How long does it take to for Methadone to leave one's system

Discussion in 'Methadone' started by diffs, Oct 2, 2010.

  1. diffs

    diffs Silver Member

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    Swim was wondering how long it takes for trace levels of Methadone to leave the body. Swim's dog has a urine drugs test in a few days and somehow some Methadone got into his dog bowl and he drank it. Swim would like to know how long(ish) it takes for Methadone to leave his dogs system, so that it doesn't show up in the urine sample? Swims dog has been prescribed dihydrocodeine so the vet will be expecting opiates to show up, but will a standard urine drugs test differentiate between different opiate substances?
     
    Last edited: Oct 2, 2010
  2. PsychoActivist

    PsychoActivist Palladium Member

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    The half life of Methadone is 24-36 hours but it can be detected in a urine screen for up to 7 days. And as little as 1-2 days. It varies depending upon how heavily the drug has been used and also on ones physiology.
     
  3. Solinari

    Solinari Titanium Member

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    At a methadone clinic for example, the drug screens look for opiates (anything that can metabolise in to morphine like codeine and heroin) and methadone separately. This is because methadone is an opioid (anything that binds to the opiate receptors can be called an opioid but they are usually synthetic) and it doesn't metabolise in to morphine so the clinic or doctor will know if someone has used heroin (or a related opiate). It also looks for buprenorphine, benzo's, cocaine and amphetamines (might be MDMA though) sometimes it will include THC.

    Laboratory analysis could look for anything the doctor asks for but some tests will cost more than others so they usually just look for the basics.

    As for the time it takes to leave the system. Well it's anyone's guess really, since the half life is so long and has such a wide range that depends on various things including metabolic rate of the individual, it could take some time. It will take even longer if the person has used multiple doses in a short period of time which has a cumulative effect, some one takes another dose before the first one has left the system.

    For people on daily methadone scripts they could have god knows how much stored up in fatty tissues which could take weeks to eliminate. This is why people say methadone is worse than heroin, well technically i suppose it isn't really, it's just that withdrawals last a HELL of a lot longer and going through extended periods of withdrawal is what makes it worse.