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Snorting - How much Ritalin/Methylphenidate is too much?

Discussion in 'Concerta & Ritalin' started by eddie, Dec 11, 2010.

  1. eddie

    eddie Newbie

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    27 y/o Male from Canada
    Hello I had a dream about my friend having a dream where he was watching a movie the main character was a guy named SWIM in this movie SWIM asked his friends this question. how much do you need to snort to OD.SWIM knew he was not going to OD, but SWIM was just worried and wanted to know for the future. Before the movie SWIM said thank you to every that helps him gain the knowledge that he wants to know. Then my dream ended.
     
  2. User-126494

    User-126494 Newbie

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    Re: How much Ritalin / Methylphenidate is to much?

    From the Drugs Forum Wiki on Methylphenidate, the various LD50's are listed here:

    Methylphenidate - Toxicity

    While this doesn't list the dose for humans, it does, Mr. Hamster believes states that the LD50 for rats and mice is between 40-50mg/kg when injected IV.

    Insufflation would be fairly close to IV, but a bit less efficient depending on the sinus conditions. Both routes bypass first pass metabolism by the liver.

    A responsible hamster would never want to try to get anywhere near the LD50 of any substance.

    However, the normal dose for the IR formulation taken orally is typically 10-20mg.

    Given this, one could say that 10-20mg insufflated might be safe, but every hamster and chinchilla are different. So the best advice is to start small if taking medications in a nonprescribed manner and always remember one can always take more, but can never untake what's been taken.

    Also, take a look at this thread, this is a subject which has been discussed before:

    Ritalin dosage (snorted)

    Be safe, be well...
     
    Last edited: Dec 12, 2010
  3. sadskills1987

    sadskills1987 Silver Member

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    LD50's aside, SWIM's poo flinging monkey in a dream (SPFMIAD) said that the amount SWIY's nose is clogged has a whole hell lot more to do with bioavalibility. in any case, ritalin psychosis, which SWIY seems to have, according to SPFMIAD, wears off not as quick as SWIY would hope, but seeing as this post was written about week ago, please allow SWIY to look retrospectively on the whole experience and evaluate whether his/her experience was really worth the deafening paranoia. if SWIY does some soul searching, this psychotic episode must have been a pretty powerful lesson. HIGH DOSES OF METHYLPHENIDATE CAUSES PSYCHOSIS!!! (not going generally 'off the farm' but definitely paranoid thoughts).
     
  4. User-126494

    User-126494 Newbie

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    What critter mentioned psychosis?

    The OP was wanting to know how much was too much, and never mentioned psychosis.

    Intranasal, or insufflation has many variables associated with it including viscosity of mucosa, pH, the condition of the nasal epithilium, etc.

    For more information on intranasal ROA, the poo flining monkey should have a look at this thread in the Pharmacology Forum:

    Nasal Drug Delivery System-Factors Affecting and Applications

    It's down to more than just one's nose being clogged which can easily be remedied.

    Psychosis, is a whole other story and is associated with the abuse of psychostimulants in general, but not what the OP was looking for.

    Be well...
     
  5. SamanthaRabbit

    SamanthaRabbit Silver Member

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    At doses higher than 20mg instant release my rabbit experiences anxiety, nausea, and intestinal disturbances.
     
  6. User-126494

    User-126494 Newbie

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    Mr. Hamster wonders what 360mg would do to the poor bunny, he shudders to think.

    The hamster is curious about the intestinal disturbances experienced with doses greater than 20mg of the IR formula, and would assume it is worse if the dose is increased?

    Be interested, be well...
     
  7. SamanthaRabbit

    SamanthaRabbit Silver Member

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    Methylphenidate in general causes extreme intestinal disturbances for my rabbit, more so Ritalin IR than Concerta XR.

    My rabbit performed a test over Thanksgiving break and didn't take her methylphenidate because she didn't have work or school responsibilities and her system kind of corrected itself.

    Now that my rabbit is taking Concerta a few days a week again it is irregular again, to the point where she may have to look for another medication all together :( It however, isn't as severe as when she would take Concerta in the morning and Ritalin at 4pm.