I recently used Kratom in moderate doses to take the edge off the end of a long Suboxone withdrawal. For this purpose, it was excellent. I had never read any reports about being Kratom being dangerous, other than some people becoming addicted. Anyway, after pissing dark urine through the second week of use I became concerned and went to the ER. My liver enzymes were off the charts. I also had no record of liver problems and never showed elevated liver enzymes on blood work. I go to see a GI specialist on Monday and hope my liver is recovering. After this incident, I found that there are frequent reports of liver damage associated with kratom on the forums. A very small minority, and most seem to have had some pre-existing liver stress. Some, like myself, had no record of liver impairment, but each person is unique. I am not trying to get Kratom banned or freak people out. But if you've ever had an abnormal liver exam or reason to suspect your liver is compromised, use with caution. And I would suggest long term users have liver work done to ensure safety. Personally, I believe this is safe in most of the population. But the reports of people with liver damage are increasing. Please use with caution, just as you would any medication or herbal supplement. Being informed is a good thing.