Pharmacological studies repeatedly point to there being no issue of physiological tolerance when prescribing Xyrem (GHB) to patients for long-term use. This is all well and good if you are seeking to take GHB in pharmacological doses in order to knock you out for sleep at night. This is not so well and good if your lab monkey prefers to take repeated, smaller doses throughout the evening in order to enjoy the euphoric and prosexual buzz that G offers the recreational user. Experience shows that, after using G in this way for an extended period, the recreational user will find that they no longer get to enjoy the same buzz. Unfortunately, unlike some other substances, the solution is not as easy as simply taking more, or bigger, doses - this will only result in sending the user to sleep. I have used GHB for just over four months now and has found that the effects have diminished substantially since his first weeks of using. His dosing pattern has been this: 1 month of almost daily evening use (repeated (x5+_) small doses (1.5g+_) taken over the course of the evening) 10 days +_ break while awaiting new delivery for conversion before continuing use as before He must also advise that each evenings' use is usually combined with smoking mj so he would be interested to hear from people who's lab monkeys do not use GHB with mj to see if that has an effect on the diminishing buzz. Please post your observations regarding regular GHB or GBL use. State what dosing pattern is used over what period and subjective experiences resulting from this use in respect to loss of quality high.