Drug info - Low dose melatonin improves sleep in healthy middle-aged subjects

Discussion in 'Downers and sleeping pills' started by Bajeda, May 9, 2007.

  1. Bajeda

    Bajeda Super Moderator Platinum Member & Advisor

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    A new entry has been added to Drugs Archive

    Description: We studied the effects of single evening doses of melatonin (0.3 mg and 1.0 mg orally) on polysomnographically measured sleep in 15 healthy middle-aged volunteers, using a placebo-controlled, double-blind, cross-over design. Compared to placebo, the 1.0 mg dose of melatonin significantly increased Actual Sleep Time, Sleep Efficiency, non-REM Sleep and REM Sleep Latency. These data are consistent with the hypothesis that low dose melatonin has hypnotic effects in humans.

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