1. Dear Drugs-Forum readers: We are a small non-profit that runs one of the most read drug information & addiction help websites in the world. We serve over 4 million readers per month, and have costs like all popular websites: servers, hosting, licenses and software. To protect our independence we do not run ads. We take no government funds. We run on donations which average $25. If everyone reading this would donate $5 then this fund raiser would be done in an hour. If Drugs-Forum is useful to you, take one minute to keep it online another year by donating whatever you can today. Donations are currently not sufficient to pay our bills and keep the site up. Your help is most welcome. Thank you.

Drug info - Lyrica and Neurontin do they hv the same effect?

Discussion in 'Various drugs not covered by other forums' started by Davevanza, Feb 26, 2012.

  1. Davevanza

    Davevanza Silver Member

    Reputation Points:
    Oct 24, 2009
    from Australia

    I've just come back from Indonesia, spending 3mths overthere.
    Tramadol, in Jkt is an OTC med.
    And there are about 25 generic of it.

    I bought some of it, and using it 200mg SR twice a day.

    ( Strangely, Panadeine with Paracetamol 500mg + Codeine Phosphate 8mg is a controlled drug over there, but Tramadol is an OTC med. Quite the opposite to what there is in Australia.)

    I've been seeing my Psychiatrist and Neurologist in Sydney for years.
    With diagnose : Anxiety, Nervous Tension Headache resulting pain behind my eyes

    I've been taking Tramadol 200SR twice daily, Clonazepam 2mg/day, and just recently my Neurologist prescribed Lyrica 75mg twice/day.

    My question is :

    1. What is the difference between Lyrica and Neurontin?
    2. Which one, according to those who have used both meds, is better ?
    3. Now with 75mg twice/day, I really don't find any effect from Lyrica. I read from internet, that when used in higher dose, Lyrica will cause drunkeness like having a beer or two. Does Neurontin in higher dose do the same thing?
    ( I know both meds will cause somnolence, ataxia, etc)
    4. I have another appointment with my Neurologist on 20Apr 2012, quite a long wait, so I went to the nearest GP, and asked for Neurontin 300mg. Will Neurontin have the same effect as Lyrica? ( I also read that Neurontin has a greater tolerance, meaning that, it has to be taken in escalating dose to get same effect, and its bioavailability is low compared to Lyrica). I also read from those using Lyrica, they say that it works better. But in contrast, I also read those using Neurontin say that it works better for them.
    So my question is, for those who have used the 2 meds, can you please give advice so i can decide whether I should stick to Lyrica, or change to Neurontin ?


  2. DiabolicScheme

    DiabolicScheme Titanium Member

    Reputation Points:
    Apr 5, 2010
    from U.S.A.
    Pregabalin is a improved formula based on gabapentin that has a much better Bio availability (absorption ) and because of this you need less of pregabalin than you do gabapentin.

    So Lyrica is superior to Neurontin.

    I also believe that gabapentin gets poorer and poorer absorption the more you take, pregabalin does not suffer from this drawback.

    Gabapentin is better absorbed with food whereas pregabalin is better suited for an empty stomach.
    Last edited: Mar 16, 2012