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Experiences - MDAI (5,6-methylenedioxy-2-aminoindane) Experiences

Discussion in 'Research Chemicals' started by Terrapinzflyer, Aug 21, 2009.

  1. Terrapinzflyer

    Terrapinzflyer MDMA, RC & News Forums

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    Please add your experiences with MDAI here. Please add dosage, route and duration to the top of your post like this:

    Info about this drug (other than experiences) should be discussed here: MDAI Drug Info Page

    When posting a experience, please describe:
    • body weight & gender
    • dose taken
    • route of administration
    • Setting: in what environment it was taken.
    • duration of main effects
    • main effects
    • side effects
    • after effects
    • rating of the experience
    • any other valuable information

    ________________________________________________________________________________________________________________________________

    Turtle is not aware of this being in the wild but hopes maybe a lucky labrat will come along to share their experiences.
     
    Last edited: May 9, 2010
  2. chillinwill

    chillinwill

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    These are not Red Rock's reports, but reports from some other people on other forums so I do not have a lot of the details such as age, weight, gender, etc. Figured since not many experience reports are available on here, might as well add as many as we can.

     
  3. acolon_5

    acolon_5 Gold Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    SWIM a 260lb male snuffed 75mgs of MDAI around 1:00pm

    For the first few hours there was a clear headed feeling, slightly euphoric, very pleasant. Mental abilities were not impaired. This material would combine nicely with amphetamines or M1/B1, SWIM thinks. No sexual push was noted.

    ~3 hours after ingestion a powerful urge to sleep overcame SWIM. He found himself in the bathroom at work asleep for about an hour before noise woke him up. This is extremely uncommon and was attributed to MDAI. Sleepiness lasted for a few hours after waking up.

    No after effects other than incredible drowsiness.

    Not interested in repeating without some stimulant to combat the drowsiness.
     
  4. beejee

    beejee Newbie

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    Re: MDAI questions?

    smoked in a joint - 50mg (sat around, and watched tv, enjoyable....but he always enjoys a nice south park.)

    chased the dragon - 100mg (walked around uni halls, felt slightly light headed, and almost a slight false sense of enjoyment, feels the effects were most prominent this way)

    gel caps - 235mg (went sledging in the snow with a few mates, fun and enjoyable....though it was the first time it had snowed for a good few years, so not really suprising swim would enjoy it. However, around 3 hours after popping the gel cap, swim insufflated a small line of drone, enjoyed the comeup whilst with his close mates, and continued to the local, swim was full of anxiety in the pub, and also struggled to sleep that night - swim assumes this is the mix of the drone and mdai.)

    swim thinks gel capped with another suitable chosen chemical might produce some interesting effects, as mdai is too subtle to be used on its own to great effect.
     
    Last edited by a moderator: Nov 1, 2010
  5. RoboCop

    RoboCop Platinum Member & Advisor

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    Re: MDAI questions?

    MDAI is not like MDMA, Methylone, or any of the beta ketones. I don't think people that are looking for a good intoxicating drug experience will like this one too much. Its a very odd compound. The euphoric intoxicating effects/feelings are subtle however the effects ARE NOT. If that makes any sense. Swim found doses between 80-217mgs to be very effective. Swims first experience was at 217mg and when it hit swim regreted taking so much and had a little fear.(only at the peak because it was a never previously tested substance.) So it was very active to say the least, swim was looking for a methylone/mdma like high and was greatly dissapointed the first time. Pupils became heavily dilated, colors brightened, swim did not like the effects and regreted buying a sample of the compound. That is until swim experienced the compound more. which once swim understands it more and knows what to expect for swim began to love it for what it is. The effects of MDAI are incredible hard to describe its very odd and hit or miss for swim. Some experiences were dissapointing and some were amazing.

    Swim personally... loves mdai. Swim however has gotten to the point in life that the most subtle backround substances are his favorite. Swims evolved past his/her dxm days, lol. I would say swims two favorite compounds are kratom and mdai.

    Both are melow, relaxing, uplifting in effects. Most of the time swim finds mdai a very chilled out, uplifting substance with aphrodisiac qualities. But this substance is different everytime swim takes it. By that I mean the main effects are usually the same but swim has found on occasions that is lacking any depth. On other occasions it was very deep even spiritual to swim and swim loved being able to experience it. Once it enhanced swims connection with swims lover IN EVERY WAY, touching felt amazing, swim felt in sync with their partner, swim was very horny and could have sex forever, swim felt a deep heart connection. This was with someone swim loves. Orgasm was hard to acheive. Another time it killed swims sex drive and swim wanted to just chill and erection was harder to get than usual and orgasm came quickly. The weird thing is these didn't have ANYTHING to do with the dose to swim, they were all 80-216mgs and at the same exact dose it can vary in the ways I mentioned previously. The main "MDAI feel" always being there. Swim has accepted that this is an odd/unusual/lovely compound. Swim takes MDAI to experience what ever it has to offer at the time. Swim feels this compound unlocks possibilitys within your mind at the time, it doesn't push you into a certain feeling or direction.

    To some it up:

    A very chilled out subtle substance that for swim is without a doubt THERE. No possible placebo effect here people, its just not what you will expect. It is what it is. 90% of the time it makes Swim quite horny. Its not streetdrug like at all... its to unreliable. its more of a tool. And I bet this compound has possible medical uses (maybe an anti depressant, aphrodisiac, or other)

    Im sorry for the long post I hope this helps some people out there I REALLY tried but this compound is just so hard to describe. Swim is still experimenting with it and will have more to say in time. Swim will take it in the future but mdai has no morish or addictive qualities. If swim could no longer get the compound swim would feel dissapointed that he/she no longer had a tool, but that would be it.
     
    Last edited: Jan 9, 2010
  6. benzup!

    benzup! Silver Member

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    Re: MDAI questions?

    swim thinks this substance is a bit too expensive to just provide a 'backdrop' setting. 230mg was taken in a gel cap on a very heavy days snowing, so swim and a couple of his mates went sledging in the dark, built an igloo, had a couple of Js and then went back to the car to prepare going to the pub a few miles away. we all felt incredibly tired, and personally swim couldn't work out if he was experiencing anything other than feeling stoned. they all had a line of mephedrone just in case, since swim and the others didnt fancy waking up in a frozen ditch somewhere further down the slippy road. In the pub, swim felt a touch anxious since it was christmas eve and the place was rammed to the rafters. alot of his friends from the past who he had not seen in a long time were there and it all felt overly surreal, not in a hallucinogenic or delirious way, but in a 'is this all actually happening right now?' way. every conversation and minor event seemed like part of a storyline that swim had to follow in order to reach the end of the book; the last chapter always involving the task of buying some more ganja off their mate to ride into christmas day on.

    midnight, sat in the car, looking out over the prom towards the sea, now also sat with two other mates (very drunk at the time) smoking some biftas and feeling very very hypnotic; almost like he could drift off out the window on the breeze of the smoke blown through his lips. when swim returned home, he noticed something he rarely notices unless he has taken something serious: everything seemed very different. The way he saw his movement in the mirror when brushing avidly at his teeth, like it was out of time by a half a second in reality; that feeling exactly like on Trainspotting when Renton ODs and falls through the floor into his own grave whilst watching the world react to him. This was probably because his entire rooms is painted a vivacious maroon red, much like the inner lining of his coffin on the movie. He was very tempted to text his mates asking if they also felt the same, but was too mesmerized and sedated to attempt the feat. he had a very long and undisturbed sleep and woke up intact the next day, with a subtly warm afterglow, nothing visual.

    would swim recommend MDAI? yes, if only once. swim has never taken the substance since, and doesn't particularly plan to mainly due to the cost. However it is certainly one to try, just for the experience, even if it doesnt make swim want to do it again. In a weird way, much like its weird nature, it just seemed worth the effort that one particular time...

    swim is male, age 20, and weighs around 12 stone (if he's not taking stimulants, this tends to rise!)
     
    Last edited by a moderator: Nov 1, 2010
  7. ronpintx

    ronpintx

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    • body weight -- 100kg Male, 51 yrs old
    • dose taken -- 140mg
    • route of administration -- Oral
    • Setting: -- Home/neighborhood
    • duration of main effects -- 3 hrs
    • main effects -- Peaced-out euphoria (no stimulant "energy")
    • side effects -- sexuality intact -- but ignorable
    • after effects -- None besides an immediate tolerance buildup
    • rating of the experience - 7 of 10 (for depressed, stimulant haters)
    • any other valuable information

    'Great for self-therapy, managing depression. The immediate tolerance buildup is like MDMA -- it's the only thing dissapointing about MDAI. Interaction with neighbors was not "X-like" at all -- no stimulants to drive excessive talking/bonding. SWIM felt like bonding -- felt close to friends -- but was able to chill-out anyway.

    SWIM really likes this stuff -- but has no XTC experience -- so tolerance-spacing metrics must be learned so as to optimize it's potential.
     
    Last edited: Feb 3, 2010
  8. incorrect

    incorrect Silver Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    Thanks for this experience report. MDAI sounds so pleasant. It is a shame that people often take it looking for a "drug" effect and and thus they feel disappointed. It sounds like a very subtle and useful compound to have around for managing one's mood.
     
    Last edited by a moderator: Feb 12, 2010
  9. ronpintx

    ronpintx

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    RETRACTION:

    MDAI is not a treatment for Clinical Depression. SWIM apologizes if he seemed to suggest that. Please seek professional treatment for any sign of Clinical Depression.

    SWIMs earlier comments about MDAI and depression was aimed at those with emotional depression/trauma. MDAI does alter serotonin levels -- next-day recovery may involve more depression for many. SSRI's -- and any other head-meds -- should not be mixed with MDAI.

    Still, for those who disdain stimulants but like that M1 rush -- it's a good alternative.
     
    Last edited: Feb 18, 2010
  10. hX_

    hX_ Titanium Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    SWIM would not recommend insuffating this substance. 100mg was EXTREMELY painful and uncomfortable for about 10-15 mins and had very little effect.

    200mg bombed however may have been a bit too high of a dose. Great snug, happy and content feeling, slight urge to chat shit but controllable and next to no classic stimulant side-effects.
     
  11. Earlybird

    Earlybird Silver Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    My friend bombed 200mg MDAI
    Onset: 20 min
    Peak: 90 min
    Comedown: 90 min

    My friend said it was like this: tingling sensation on the skin, felt talkative and urge to bond, but controllable. Semi-surreal sensation, kind og like smoking pot, without losing your wits and getting silly. Heart rate increase with some mild sweating. Very pleasant indeed. Comedown was easy. Worth the try.

    Negatives: two short involuntary eyelid twitches during peak, large pupils at peak

    My freind said he will be doing trying this again.
     
  12. cantstoptalking

    cantstoptalking Silver Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    Swim 90kg
    Male
    Fit healthy, lots of exercise.
    Swim has had a crazy day mixing very small amounts of NRG1 with MDAI. No scales I'm afaid so eyeball doses. Roughly 100mg of MDAI with about 6 cous cous sized of NRG1.

    Swim has bombed 6 of these over the course of the day and has had a wonderful time. Very pleasant indeed.

    Swim understand that the Naphyrone should cancel out MDAI effects but swim enjoyed the blend. Swim has not tried MDAI with Amphetamine to compare though.

    This is my first post so sorry if its in the wrong place.

    Swim had no heart issues from NRG1. Swim also insuflate some finely ground MDAI with no pain at all.

    Hard to say lenghth of effects due to multiple doses.
     
  13. source

    source Palladium Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    SWIM tried 0.5g MDAI in .20mg doses (every hour) after finishing off .5g NRG-1.
    SWIM found MDAI to be very painful nasally and would advise oral administration.
    Effects began around 5-10 minutes after insufflation, and were gradual. No initial rush like 4-MMC. SWIM began to feel lightheaded and euphoric, and after a while began to feel very talkative and appreciated music.
    SWIM feels main effects are much like mephedrone. After administering most of SWIMs .5g, SWIM experienced redness of hands/knees, forgot what she was talking about halfway thru a sentence, confusion, and the infamous eye jitters & involuntary eye movements.
    Today SWIM has no major comedown, head feels slightly fuzzy and she is just a little tired. SWIM takes 2x 50mg 5-HTP daily.
    SWIM enjoyed her experience of MDAI and will definately try again without NRG-1 first to see what it's like on it's own.
     
    Last edited: May 2, 2010
  14. MrG

    MrG Silver Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    Please be wary of combining this drug with certain stimulants.

    http://www.ncbi.nlm.nih.gov/pubmed/1726189
    Abstract
    There is increasing evidence linking dopamine (DA) to the long-term serotonergic (5-HT) neurotoxic effects of certain substituted amphetamines such as 3,4-methylenedioxymethamphetamine (MDMA). The present study was undertaken to examine the importance of DA metabolism, uptake inhibition and release in the long-term effects of these drugs by combining various dopaminergic agents with an analogue of MDMA that had low neurotoxic liability, namely 5,6-methylenedioxy-2-aminoindan (MDAI). Monoamine and metabolite levels and the number of 5-HT uptake sites (using [3H]paroxetine binding) were determined 3 hours or 1 week after treatments. Combining the monoamine oxidase inhibitors, clorgyline (MAOA selective) or deprenyl (MAOB selective) with MDAI did not result in any long-term reductions of serotonergic markers. Similarly, combining the DA uptake inhibitor GBR-12909 with MDAI did not result in any long-term changes in monoamine levels at 1 week. In contrast, a single pretreatment of posttreatment with the nonvesicular DA releaser S-amphetamine and MDAI resulted in small but significant long-term changes in monoamine levels. More importantly, if a subacute dosing regimen (every 12 hours for 4 days) was utilized, the combination of S-amphetamine with MDAI resulted in a marked long-term decrease in the levels of cortical, hippocampal and striatal 5-HT, 5-HIAA and the number of 5-HT uptake sites. The results are discussed in terms of the significance of DA and especially nonvesicular DA release in the long-term effects of MDMA-like drugs.



    At first glance it looks as though Dopamine re-uptake inhibitor drugs are not a problem in combination with MDAI but Dopamine releasers are. As for those that both inhibit re-uptake AND stimulate DA release, there could be a cause for concern. My worry is that, with MDAI being touted as a proven non-neurotoxic drug, Joe Public is going get reckless with combining it with any and all stimulants in order to try and recreate an MDMA-like experience.
     
  15. yaniczka

    yaniczka Silver Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    does this mean that its more dangerous to mix methylone with mdai then to mix methylone with mephedrone or taking only methylone on its own? thks.
     
  16. MrG

    MrG Silver Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    It's not entirely clear at this stage. Don't forget that this research relates to Rats, not humans. My understanding is that Mephedrone, being a more potent DA inhibitor/releaser would be the worse choice to combine with MDAI compared to Methylone, but there is insufficient data to be able to objectively say what would be safer in combination or on it's own.

    It would be worth studying more about the whole Dopamine Neurotoxicity issue in and of itself. In the meantime I would remind users that, if they are going to take any of these substances, the goal should always be to take as little as possible.
     
  17. lineartransform

    lineartransform Titanium Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane

    No. The mechanism of neurotoxicity is hypothesized to be a result of simultaneous dopamine and serotonin release. However, serotonin release and blocking dopamine reuptake only does not appear to cause these neurotoxic effects.

    Methylone and mephedrone are both dopamine and serotonin releasers - risk of neurotoxicity is prevalent. MDAI is only a serotonin releaser - in conjunction with dopamine releasers it will also be neurotoxic.

    One would not be more dangerous than the other - they both have a similar risk profile.
     
  18. SparkyMarky

    SparkyMarky

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane Trip Reports

    Hello fellow psychonauts!

    Well, SWIM finally managed to get hold of some MDAI this week: 2g of a moist, clumpy, coarse brown powder that turned dark rusty red with Marquis reagent. So far, so yay!

    A bit of background:

    Swim's a 40*mumble* years old male, weighs about 70kg and has been using methylone for the past year in the absence of any Mandy (MDMA) or pills containing Mandy. SWIM's never tried mephedrone (he doesn't like the sound of it in lots of ways) and has been looking for chems that could, at least in part, recreate that old Mandy magic. Methylone's nice, but doesn't have the same degree of entactogenicity or empathogenicity. He'd heard that MDAI was a nice, gentle, touchy-feely chem that didn't have methylone's stimulant properties - particularly its ability to stop him sleeping for hours and hours - so it seemed like an ideal candidate for a test-run.

    So....

    Last night SWIM climbed into the driver's seat of his moist, brown MDAI-mobile. He decided to go with an initial eyeballed dose of about 100mg. SWIM uses 200mg gelcaps to measure stuff out and so he roughly half-filled a cap (although, due to the sticky, coarse, clumpy nature of the MDAI, he suspects he didn't have quite 100mg). And having had good experiences with squizzing methylone up his bum - not to mention it being a more economical way of taking chems - he dissolved it in some warm white wine (classy, eh? SWIM had read that MDAI doesn't dissolve well in water, but dissolves better in alcohol) and squizzed it up there with a small, plastic pet syringe, and then started fannying around on the PC, waiting to come up.

    T+ 60 mins: nothing, really. Made some mild warmth, but SWIM suspected that was just placebo and expectation. And maybe the wine! (Not really - 10ml of white wine, even up his bum, is unlikely to do much!)

    T+ 90 mins: hmmmm.... still nothing. Dissolved another eyeballed dose of 100mg in some more white wine and swallowed it.

    T+ 120 mins: nope. Nothing. SWIM's feeling a bit disappointed now. He'd been hoping for *something*, even if MDAI is suppose to be fairly subtle compared to methylone.

    T +150 mins: hmph! Bah! Still nothing. Deciding not to let the whole evening go to waste, but not wanting to throw any more MDAI down his neck or up his arse - not tonight, anyway - SWIM squirts 100mg of methylone up his backside and hopes it's not going to be one of those nights where his body just seems to stand there with its arms folded, saying: 'Not tonight, sunshine!'

    T+180 mins: aaaaah! That's more like it! Sadly it's a classic methylone high, with nothing else that might indicate that MDAI is coming out to play.


    The rest of the evening was very nice, but purely a methylone evening.
    Trying to sleep, at about T+ 540 mins, was hard but he managed it in the end. As is usual, for SWIM, with methylone. And today, SWIM feels fine if tired, again as he does with methylone.


    Conclusion: SWIM is *very* disappointed in his first MDAI experience. No noticeable effect from it in any way. SWIM thinks that the dampness of the MDAI probably meant that there was a lot less actual MDAI in his purchase. On another thread here, someone else tried drying out *his* MDAI (which matched the description of mine) and found that it lost a ridiculous *40%* of its weight. What a rip-off, eh? Which probably means that SWIM only took about 160mg or so of actual MDAI into his body, in two installments of 80mg, which are pretty low doses by some people's standards. And the ability to measure it accurately because of it's sticky, clumpiness, means that he probably had even less than *that*!

    Next time, SWIM's going to dry his MDAI out to give him a better idea of how much he's actually taking, and swallow it rather than faffing about with wine and his bottom, just in case it didn't dissolve well. Fingers crossed for SWIM!


    Sparky
    xx
     
  19. jonboi

    jonboi Silver Member

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane Trip Reports

    this is swims tapirs first, tryin to giv a bit back since discovery of RCs so forgive any errors.
    MDAI 2g
    male 26 14st
    female 22 10st

    drug history: lots of high quality cocaine, mephedrone other illegal stimulants.
    setting: the tapirs hous with friends.
    Note, the tapirs are frequent re-dosers so comments re craving not for all.

    appearance, light brown power bought online.
    aroma, not offensive but unpleasant.
    alcohol male- 1 or 2 vodkas, her nothing
    sniffed c. 100mg each.
    15mins mild effect - am allways dubious.
    30 mins - twitchy mild head buzz.
    45 mins 2nd line each
    1h30 actually start to nod off talking to friend. body buzz but head feels lethargic.
    1.45 another line c.150mg girlfriend is feeling effects both twitchy but chatty enjoying music etc.
    girlfried is really struggling to snort eyes watering etc.
    she levels out and we continue until 2/3 of a gramm left.
    4.00at this point the male tapirs legs are crazy and GF is glued to iphone.
    4.05 cant p*ss, and not like E cant p*ss, not even like mdma cant p*ss. The tapir cannot go to toilet.
    4.30 we mix remaining with small amount water and lime and neck.
    5.00 friends leave.
    5.15 still no pee, gf buzzing.
    5.30 body rush, shaking, cannot walk down stairs as legs going crazy.
    6.00 finally pee.
    and on....... it was the headrush of 1 or 2 good E with the body f*ck of ketamine.

    unpleasent to sniff, and as soon as the tapir had peed he couldnt again for another 2hrs, which ruined it.
    gf thought ok.

    summary - will not be buying again, but if you love twitiching go for it
     
    Last edited by a moderator: Apr 30, 2010
  20. SparkyMarky

    SparkyMarky

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    Re: MDAI 5,6-Methylenedioxy-2-aminoindane Trip Reports

    Well, after his first disappointing ride in the MDAI-mobile the other night, last night SWIM thought he'd give it another go.

    Specs:
    male, 47, 70kg. Previous experience with methylone and spliffs.

    SWIM dried the MDAI out a little bit on the radiator and then dumped about 200mg (the previous trip involved two doses of a-bit-less-than-100mg, spaced out by an hour and a half or so) into some lemonade (turning it a most unnattractive shade of mud-brown) and swallowed it down - no noticeable taste - and sat back to wait for the engine to fire up.

    And waited...

    And waited....

    Two hours later, SWIM was *still* waiting.

    Bah!

    Went to bed after another couple of hours and slept fine - although I woke up a few times during the night, feeling a wee bit groggy (as though I'd taken some Nytol), although I've no idea whether that was actually due to the MDAI.


    SWIM's feeling a bit disheartened by this. Two trips and nothing. Nada. Zilch. This morning he received 2g of MDAI from the supplier that had previously sent him methylone by mistake (it's lighter brown than his first lot, and much more powdery and dry, so hopefully it isn't mainly water!) so SWIM's going to keep going with it until a) he actually gets something from it, or b) he runs out.

    Does anyone think SWIM's doing something obviously wrong? Or could it simply be that MDAI's not the chem for him? When he first tried methylone, he got absolutely nothing from it on his first couple of trips for some reason, so SWIM's hoping that it's the same with MDAI.

    Sparkyxx