Drug info - Methylone and Methyl-K

Discussion in 'Beta-Ketones' started by enquirewithin, Apr 5, 2005.

  1. enquirewithin

    enquirewithin Gold Member

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    Are methylone 2-methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one) and methyl-K2-METHYLAMINO-1-(3,4-METHYLENEDIOXYPHENYLPENTANE related?
     
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  2. gn2osis

    gn2osis Iridium Member

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    They aren't the same and aren't going to be very similar in effects, if
    that's what you're wondering. Methyl-K has a five-carbon chain
    hanging off its phenyl ring, whereas methylone has just three (as does
    MDMA, but methylone also has has a keto group on the carbon attached to
    the phenyl).





    Methylone structure
    [​IMG]


    Methyl-K Structure
    [​IMG]

    Shulgin made a whole bunch of analogs of MDMA, including the two you
    mention, and none managed to surpass MDMA in terms of subjective
    effects. Adding a carbon to MDMA's three-carbon chain gives MBDB
    aka methyl-J, which has some nice qualities but is felt by most not to
    be as nice as MDMA. Adding one more carbon gives methyl-K, about
    which Shulgin noted:





    And here, Shulgin talks about the logic behind the design of methylone:
    http://www.cognitiveliberty.org/shulgin/adsarchive/cathinone .htm


    Edited by: gn2osis
     
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    1. 4/5,
      Informative post
      Jan 1, 2010
  3. enquirewithin

    enquirewithin Gold Member

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    Thanks[​IMG]-- that's very informative. I did not know that Shulgin had designed it, but sure enough it will be in the third book!


    (Certainly Methyl J comes nowhere near MDMA in subjective effects.)






    Edited by: enquirewithin
     
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