Combinations - Methylone and SSRI’s

Discussion in 'Beta-Ketones' started by TimRog, Jul 25, 2005.

  1. TimRog

    TimRog Newbie

    Reputation Points:
    0
    Messages:
    8
    Joined:
    Dec 13, 2004
    Hey everyone.

    Quick question. I've been on Lexapro (an SSRI) for about 6 months now and
    recreationally all I've been really 'doing' is some prescription opiates and
    benzos. (And a little ambien now and then.)

    I've done Methylone in the past, BEFORE I was on Lexapro (an SSRI).

    Question is: Can I still enjoy Methylone even though I'm on an SSRI? Will it
    totally not work at all? Or just have diminished effects?

    Thanks for any help anyone can give.
     
    Last edited by a moderator: Apr 28, 2008
  2. Softrat

    Softrat Newbie

    Reputation Points:
    0
    Messages:
    217
    Joined:
    Apr 18, 2005
    I'm not sure, but it might kill you.[​IMG]SSRI drug stop Seritonin from being taken up as well. Methylone dumps huge amounts of seritonin into your brain. Sounds like a recipie for seritonin poisening to me.[​IMG]
     
  3. Softrat

    Softrat Newbie

    Reputation Points:
    0
    Messages:
    217
    Joined:
    Apr 18, 2005
    By the way this statement applies to any and all psychedellics as they all increase seritonin levels. But Methylone and it's relatives really increase seritonin a lot.
     
  4. oldman

    oldman Gold Member

    Reputation Points:
    248
    Messages:
    510
    Joined:
    May 17, 2005
    I onec read here that if you're on a ssri you out to really consider if you're of a sound enough state to deal with the after effects of mdma, methylone, etc. so I made sure I stopped taking those bullshit ssri's at once. What a bunch of beneign super pharma crap all that stuff is. you never even feel like you're on anything until you stop takling them and start going off on everyone and yourself. Wean off slow wait 6-8 weeks (I did not do this and wasted some good rolls becuase of this). then get your candy. You'll stop having those night sweats and start enjoying sex again, what a wonderful world it will be.
     
  5. radiometer

    radiometer bananadine addict Platinum Member & Advisor

    Reputation Points:
    3,376
    Messages:
    3,206
    Joined:
    Apr 13, 2005
    from U.S.A.
    ^ Excellent advice, expecially the first sentence, so I'll repeat it:

    Methylone exerts quite a bit of its effect on the dopaminergic rather than
    serotoninergic system, so it may still produce something like the
    expected effects despite taking
    SSRIs.I have not heard any reports confirming this. It would not be a
    special risk to attempt the combo, if anything it simply will not work
    correctly, as with MDMA and SSRIs.Edited by: radiometer
     
  6. timothyrogersmd

    timothyrogersmd Newbie

    Reputation Points:
    0
    Messages:
    1
    Joined:
    Dec 16, 2005
    from U.K.
    Well it worked 'ok'. but nothing magical.

    How long could i lay off my lexapro to get maybe some better effects? Would skipping a daily dose or two days help maybe?

    I just miss my methylone. :(
     
  7. nanobrain

    nanobrain Platinum Member

    Reputation Points:
    824
    Messages:
    1,095
    Joined:
    Apr 12, 2005
    from Australia
    MD, you ever try the ol' 'SEARCH' Rx?

    anyhow, M1 impacts both the 5HT2 and DA systems, the former i reckon via the same mech as MDMA - reversing SERT.

    so much of the empathogenic qualities of M1 would be taken away if administered while on an SSRI course, leaving the dopaminergic effects fairly intact.

    as seems to be the case above.

    oh, and Dr MD, lay of the SSRI's for 6+ weeks for any 'special' effects to manifest from serotonergic psychedelics.