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Methylone drug testing *experience*

Discussion in 'Drug testing discussion' started by mpr405, Jul 2, 2009.

  1. mpr405

    mpr405

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    My friend searched and searched and searched and couldn't find much at all on this topic, so he wants to post his experience to hopefully help others.

    He had ~100mg of Methylone 24-25 hours before a lab DT at his doctor's office and came back completely clean. He was worried about possible false positives with meth/MDMA but these concerns were ultimately unwarranted.

    Obviously, it's possible that my friend has a very fast metabolism and that there wasn't enough methylone in the system to trigger a positive result, but that doesn't sound very likely to him.

    Hopefully someone finds this info valuable.
     
  2. runitsthepolice

    runitsthepolice Silver Member

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    Swim reports he has gone to his UA's high on methylone on a few occasions. Swim would definitely know if he failed any of them. Methylone won't show up...in a lab test anyway.

    It was pretty funny to watch swim mack on the girl that collects the UAs.
     
  3. Jasim

    Jasim Gold Member

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    Methylone is essentially mephedrone with the MDMA dioxy ring. I'm guessing that if methylone triggers a positive for amphetamines on a drug screen, then mephedrone surely would.

    Do keep in mind that immunoassay drug screens can vary considerably and some are highly prone to false positives. No standard confirmatory panels that I have ever seen test for any of these RC's, neither methylone nor mephedrone.

    If someone comes up positive on a drug screen and was only using one of these chemicals, push for a confirmatory test. The results will come back negative, I'm 100% certain of it.
     
  4. MidtownCoog

    MidtownCoog

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    Methylone actually triggers a positive for meth on the five panels I have tested, as recent as this week.

    My next experiment is how this works on hair tests.
     
  5. Phenoxide

    Phenoxide Super Moderator Staff Member

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    Perhaps the batch of 'methylone' SWIY had indulged in really did contain methamphetamine? Has confirmatory testing been performed? If so it'd be useful to know what exactly was detected.

    Just seems a bit odd that in all the months that the cathinones were readily available in the UK there were few if any reports of false positive tests. Immunoassay tests will vary in selectivity but I doubt there has be a conscious decision to change the test to incorporate methylone.
     
  6. Jasim

    Jasim Gold Member

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    The specifics of this are confusing to me and let me explain why. Immunoassay tests are rather generalized tests that test for classes of chemicals (not specific chemicals) which may include amphetamines, opiates, cannabis metabolites, barbiturates, etc.

    You keep saying that the tests came back positive for "meth", I'm assuming you mean methamphetamine. Can you please be more specific and provide additional detail?

    As I stated, an immunoassay test will detect classes of drugs, not specific chemicals. And I have never seen an immunoassay test that would show a positive of methamphetamine. Such a test would come back positive for the class of drugs called "amphetamines". In order to distinguish and determine methamphetamine specifically, the sample would have to undergo confirmation testing. And as I have already stated a confirmation test will NOT give a false positive. If a confirmation test comes back positive for methamphetamine, then methamphetamine is in the sample. There is no other possibility.

    That would indicate one of three things:
    1. the sample was adulterated or contaminated with methamphetamine after it was taken from the subject, which I think is highly unlikely.
    2. the subject took a drug that was metabolized into methamphetamine (or in the case of other drugs, a commonly shared metabolite). Again, I think this is highly unlikely in this case.
    3. the subject took a substance which contained methamphetamine, the most likely scenario.
     
  7. ThizzKid

    ThizzKid Newbie

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    Swim is on probation and gets drug tested about once every other week. After doing some research, he decided to invest in some methylone. Swim figured that even if he failed the 12 panel test because of a false positive (for meth or MDMA), that he could just push for a confirmation test, and he would be fine. Earlier in the week, swim took about 400 mgs of this entactogenic substance. Unfortunately, swim was called in for a drug test the very next day. Swim drank a lot of water in fear of failing the test for false positives. The 12 panel test strip was dipped in the urine, and swim passed for everything on the 12 panel (which includes both meth and MDMA). Swim does not think that this is only because of all the water he drank. 400 mgs doesn't seem like an amount that would metabolize out of the body that fast, and swim's urine was not dilute. I hope this contribution helps comfort someone in a similar situation. I also hope that this doesn't mislead anyone into believing that this is always the case.
     
  8. Iftevyai

    Iftevyai Newbie

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    SWIM can attest to this as well. Having planned out in advance for a night on the town with a little assistance from methylone, he purchased a 7 panel home testing kit to see how his results came back the next day. 9 hours after SWIMs initial 300mg dose and 8 hours after his 150mg booster (he has been experimenting with dosing regimens), the drug test kit came back negative for Methamphetamine and MDMA at the testing threshold, though some metabolites appeared to be present as the negatives were weaker than, say, cocaine or amphetamine.
     
  9. RE_UP_RECORDS

    RE_UP_RECORDS Newbie

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    Its crazy that I can't find a straight answer about Methylone and if a person will fail a UA after use. There must be somebody out there that has taken a lab test and knows for sure that a false positive will be present for amphetamines. Some people say yes same say no. Which is it?
     
  10. Alfa

    Alfa Productive Insomniac Staff Member

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    This thread is quite clear about it. Did you read it?
     
  11. RE_UP_RECORDS

    RE_UP_RECORDS Newbie

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    I wouldn't say it is clear. Most people say that there is no chance of failing a test while others claim to have failed a test and swear that you will.
     
  12. Alfa

    Alfa Productive Insomniac Staff Member

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    The only one who claims to have failed is midtowncoog, who is extremely vague and claims that it tests positive for meth. This is highly unlikely.
     
  13. Phenoxide

    Phenoxide Super Moderator Staff Member

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    It's worth adding that although methylone would not be expected to cause a true positive in a typical immunoassay drug test, it may give a false positive to amphetamine, methamphetamine or MDMA. However when confirmatory testing is performed it should be apparent that none of these controlled substances are present in the sample and the positive would be struck off.

    It's also worth noting that although methylone testing is not a standard procedure some laboratories now offer specialist tests designed to detect various novel drugs, including methylone. See: Redwood Toxicology announces urine test for cathinones and piperazines
     
  14. yaniczka

    yaniczka Silver Member

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    very interesting info on here and great news about methylone not showing on the tests. however, it seems that everyone is talking about urine test. are the saliva tests (performed by police to drivers) more prone to show something or are they working similar way to urine ones? thks.
     
  15. alex7592

    alex7592

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    Alright, I've been researching this drug for several days now and I have still yet to find solid answers and tests done for the drug testing. How long does Methylone take to get out of your system? I've heard anywhere from 2 days to 2 weeks.
    If there is someone out there that can test this that would be amazing. I want to know how long it takes for the drug to clear an athletic built male. I don't know if it varies by body type or gender because it looks like no one has actually done tests. For the tests I want to know results for piss tests, blood tests, and saliva tests.
    I know this drug severly dehydrates you while you're using and a little for the next 2 days but what are some other affects done to the body. This drug sounds promising as a severe pain reliever but I will not administer if the drug is to damaging. I also know that Methylone accelerates the Kidneys and thats what dehydrates you but are there any other affects done to the internal body structure? This should be tested by someone for some answers. I don't have the resources to be able to do this.
     
  16. Iftevyai

    Iftevyai Newbie

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    A friend of mine who loves his Methylone and is all sciency and such went about doing various tests on this substance for physiological responses. Being all sciency and such he was able to produce a fair amount of M1 and to regulate the administration/purity to himself and others who volunteered to try it in the name of science. My friend has access to some advanced medical and lab equipment so he could do some rigorous after-hours testing.

    He found that none of the subjects tested in a urinary analysis tested positive at the cutoff threshold for any substance checked for in the SAMHSA-5 after 12 hours. Testing was done at varying dosing regimes, all instances totaling under 1g.

    He found that resting heart rates for individuals with a BMI under 25 increased by an average of 7-8 beats per minute for every 100mg ingested over the course of the evening. At the highest tested dose, 800mg, the subjects experienced an average of 60bpm above baseline for each individual at rest.

    He found that average body temperature was increased by 2 degrees fahrenheit while under the influence. A subject was considered to be under the influence from one half hour after ingestion until the subject was able to urinate following the final dose administered.

    He also found that electrical activity in the brain was increased above baseline in the prefrontal cortex by about 5% for each 100mg ingested, peaking out at 35% regardless of dosage.

    Most of this is irrelevant in regards to drug testing, but why not toss it out there.
     
  17. baykt

    baykt Newbie

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    I was given a random piss test yesterday afternoon, in an instant-analysis cup (6-panel), and I came back positive for amphetamines and methamphetamine. I've been dabbling in m1 for a couple weeks now, and I figured I was safe from all of the info on this page. Unfortunately, that was not the case. M1 is the ONLY rc/substance I have used.

    This was at a legit health clinic, too. Not a piddly little dipstick test. They are sending it out to analyzed by gc/ms, which I am freaking out about. M1 is not scheduled federally, however in my state it is. Are they going to call back with positive results for m1? Or negative results for amph/meth?

    I am pretty terrified.
     
  18. Phenoxide

    Phenoxide Super Moderator Staff Member

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    Some labs will set up the GC/MS tests to only look for very specific compounds (e.g. methamphetamine, amphetamine) while others may look for any controlled substances in their confirmatory tests. It largely depends on whether the forensics lab responsible has been proficient enough to incorporate methylone testing into their protocols since it became a controlled substance. It could go either way to be honest.

    It's worth remembering that much of the previous discussion in this thread dates back to before US states began legislating methylone as a controlled substance. In those cases even if the false positive to methamphetamine by immunoassay panel testing was followed up with a true positive to methylone in the confirmatory tests this would not have been an issue since no controlled substance would be present in the test sample. This is no longer the case in states where methylone is controlled.
     
    Last edited: Aug 18, 2011
  19. baykt

    baykt Newbie

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    M1 has been scheduled in this particular state just since last month, so I don't know how bad they are looking for it just yet. I guess I will find out soon. Very nerve wracking.
     
  20. baykt

    baykt Newbie

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    Just realized that my friend had posted two messages yesterday from my computer, so that wasn't me. Anyway, I just heard from him this afternoon and he let me know that his gc/ms confirmation test came back negative for amphetamines/methamphetamine. So I thought I would pass that along to everyone.

    He said he hopes this will put to rest whether or not methylone can cause a false positive for amphetamines on an instant urine test. He said he did want to point out that his usage was pretty heavy, having consumed it for roughly 6 days in a row leading up to the test. So those of you who only use it occasionally may have less problems, but he still would recommend you err on the side of caution.

    Also, while methylone doesn't show up on gc/ms as of right now, with laws banning it seemingly being enacted weekly, he can't guarantee that 3, 6, 12 months down the road this will still be the case.