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Mylan fentanyl patches- a different method?

Discussion in 'Fentanyl' started by paranoid_android, Apr 9, 2008.

  1. paranoid_android

    paranoid_android Silver Member

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    SwiPA would first like to say that he checked many threads to see if this was covered. He couldn't find it but that doesn't really mean anything. Now, onto the tek.

    It's been stated that the fentanyl in mylan patches can be extracted with solvents, even regular 80 proof spirits. It's also known that fentanyl is absorbed best transdermally (and perhaps buccally).

    SwiPA surmises that a patch could be soaked in a small amount of 91% isopropanol. The solution could then be applied to the skin with a dropper for minimal waste versus most other routes of administration.

    If SwiPA can get ahold of a used mylan patch tomorrow he will try this with part of it and report back. In the meantime, what do yall swimmers think?
     
  2. OhCasey

    OhCasey Palladium Member

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    Sounds interesting, I cant wait to hear your results.
     
  3. lightworker

    lightworker Newbie

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    SWIM has these Mylan 75 Patches. The ones without the Gel. Just thin and Flat. SWIM wore one for 3 day... didnt feel anything. Put on another one about 1 Pm yesterday. Still doesnt feel anything now. SWIM has one patch left. And Wants to know if cutting it into strips and putting it in between my cheeks and gums would work. Or this alcohol method, because SWIM has 91% iso Alc...

    SWIM has an opiate tolerance of about 100 - 140 mg oxy.
    All help appreciated.
     
  4. Matt The Funk

    Matt The Funk Silver Member

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    Wearing the patches was a mistake. SWIM thinks cutting them into 1/16ths and figuring out your dosage from there (SWIM figures it to be about 20mg of morphine).
     
  5. lightworker

    lightworker Newbie

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    yeah LW shouldnt of put the patches on, LW read around and found out that the Mylons are only good for under tongue or gums and cheeks. So LW cut them up into 12ths. And sucked on 2, LW feels alright, pretty relaxed. LW doesn't know if its from the herb LW smoked earlier, but probley not. LW will try 2 more under the tongue at 6. When SWIY says 20mg of morphine in each little square. LW cut his into 12 pieces. LW is sad he wasted 2 other patches... Oh well. Any Way to smoke these? Vaporize? Appreciate it:)
     
  6. Matt The Funk

    Matt The Funk Silver Member

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    Oh they're 75mcg....SWIM didn't notice. Anyways it might be a little closer to 15mg when cut into 1/16ths. Since they were cut into 1/12th's....SWIM is guessing SWIY is getting about 45mg equivalent. Tolerance builds up to these VERY fast...so if SWIY isn't an opiate addict (even if one is) SWIM highly discourages to continue using them if there is only 1 patch left, and saving it for the weekend or something. There is no way to smoke or vape these particular types of patch that SWIM knows of. Be careful with em too, SWIM ended up taking about a whole patch (doesn't remember but is somewhere in another fentanyl thread) along with some darvocet and adderall XR, and of course dank herbals, and went to the opiod nod-hallucination land. Also just to give SWIY a little knowledge on his tolerance, it was a lot lower at the time (2 months clean when the hallucinations happened), he likes to take about 5/12ths or so over the course of 1 1/2 hours. But that's just how he use to do it. His tolerance to something more accurate in dosage would be....probably 100-150mg of hydrocodone for that same feeling (although hydrocodone effects him a lot stronger than other opiods and is his favorite). Hope this post helps.
     
  7. OhCasey

    OhCasey Palladium Member

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    If you do wear them swim suggests hitting them with a blow dryer or putting a heating pad on them. Just be careful as it will release alot more of the ingredients alot faster and swiy will drain swiyour patch in 1-2 days. Also this works for both the mylans and gel ones but seems to work better with the mylans.
     
  8. Orchid_Suspiria

    Orchid_Suspiria Newbie

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    Just take a hot shower or bath.This is a foolproof method to get fentanyl patches to work much quicker.Swiy shouldn't be eating fentanyl.Eating plastic laced with fentanyl and other chemicals just can't be good for a person.
     
  9. Psych0naut

    Psych0naut Platinum Member

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    SWIM has had Durogesic patches in the past, which don't contain gel either. He always cut the righ dose off of a patch with his scissors, and stuck it underneath his tongue, and chewed on it 5 minutes later, to release all the Fentanyl from the plastic matrix. It's really important to keep the bit of patch in ones mouth for 15 minutes or so, of which 10 minutes one has to be chewing on it, to release all the Fentanyl.

    Extracting the Fentanyl will work well too. Around 98% of the Fentanyl in a Durogesic patch can be extracted by letting it soak in strong liquor overnight. This has been tested with quantative analysis, and the 98% percent yield is a true percentage. Janssen-Cilag's rivals claimed that Durogesic had the same abuse-factor as gel-based patches, so they proved it by doing an extraction on them with easilly obtainable chems, in this case, strong drinking alcohol, namely wodka and rum. SWIM has explained how to perform this extraction to yield a safe solution in several other threads, so UTSE to find it.
     
  10. Matt The Funk

    Matt The Funk Silver Member

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    You never actually eat the plastic....
     
  11. lightworker

    lightworker Newbie

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    MYLAN sucks pretty bad. SWIM sucked on them, chewed them, everything. Nothing special... LW much rather buy some herb and chill. LW will wait for the other patches with the gel inside... Otherwise MYLANs aren't worth it in LW's opinion. Unless LW was getting them fairly cheaper. Thank SWIYou for all the help.
     
  12. OhCasey

    OhCasey Palladium Member

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    dont swallow your spit
     
  13. Matt The Funk

    Matt The Funk Silver Member

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    Yeah.
     
  14. paranoid_android

    paranoid_android Silver Member

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    SwiPA has been thinking about a slight change to this method for a while, but hasn't had a chance to get a patch. It's very likely SwiPA will obtain one tomorrow, and if he does then part of it will be extracted with a solvent. Now onto the tweak.

    It came about when SwiPA was thinking about how runny the solution would be. It could spill or run off if not applied properly. Then he realized there is a perfect little receptacle for this sort of concoction: the belly button.

    SwiPA is anxious about possibly wasting fentanyl, so if he finds buccal/sublingual routes to work very well for him, he might not risk an extraction. Still, he seems very intrigued by the possibility of "navel administration".
     
  15. OhCasey

    OhCasey Palladium Member

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    The thought of naval administered fentanyl makes me shiver. I guess I'm just weird about my belly button.
     
  16. paranoid_android

    paranoid_android Silver Member

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    SwiPA just realized that there is a penetrating agent involved in the patches. Regular isopropyl might work as such a catalyst, and it might not. Either way, yet another new addition to this popped into my head:

    If a potent, homogenized solution of fentanyl was mixed consistently with benadryl (diphenhydramine) anti-itch cream, the end product could be an all-in-one "nod cream". Of course, great care would be needed to ensure a standard potency throughout the cream. If several patches were used and the cream was placed back in the benadryl tube, it would be a very discreet and portable way of getting high.

    Any thoughts?
     
  17. Matt The Funk

    Matt The Funk Silver Member

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    Death.
     
  18. OhCasey

    OhCasey Palladium Member

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    With no way to test potency or make sure the fentanyl was equally distributed it would be dangerous to make a large quanity.
     
  19. Psych0naut

    Psych0naut Platinum Member

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    Both Durogesic(gel-less patches) and Duragesic(gel patches) contain ethanol as solvent, so I assume Mylan patches contain ethanol as solvent as well. SWIM thinks there is a pretty clever mechanism in those patches, because it takes a while (around 3 hours) after putting them on one's skin before one feels the Fentanyl having effect. SWIM doesn't think that dripping extracted Fentanyl dissolved in ethanol on one's skin wouldn't neccesarily get absorbed transdermally. Remember there's a pretty clever mechanism in those patches, which causes it to take around 3 hours before one feels it taking effect. One would expect that dropping a concentrated solution of Fentanyl dissolved in a suitable solvent like ethanol on one's skin, would cause effect in 15 minutes, 30 minutes max. Certainly not 3 hours. I think the reason why it takes so long for patches to achieve a high enough serum level for one to feel the Fentanyl pretty strong, is because of the special mechanism the patches work through. They build up a reservoir of Fentanyl just under the skin, where it starts to pool up and get's larger and larger in volume untill it has spread so much that the pooled up subcutaneous reservoir of Fentanyl spreads around a vein or several veins, or some capilaries where it enters the bloodstream and get's carried to the brain. It pretty clear why it takes so long before a Fentanyl patch starts to give any noticeable effects after having it put on to the skin. The rate at which the patch gives off it's Fentanyl stay's the same, no mather what(only temperature can control this rate) The rate at which a Fentanyl patch normally gives of it's Fentanyl is relatively slow, depending on which patch one has; 12.5mg/25mg/50mg/75mg/100mg per hour. This is generally plenty enough once the reservoir underneath one's skin has pooled up well enough so that the Fentanyl get's absorbed directly from the patch on one's skin, through the subcutaneous reservoir into the bloodstream. But ofcourse at such a rate, it does take some time before enough Fentanyl has pooled up under one's sking to have reached a/some vein(s) or capilaries. Those patches might take a long while to full work after they've been applied to the skin, but they do get a wopping 92% bioavailability, which is truly massive.

    But back on topic, enough explaining about how a Fentanyl patch works ... Because of the cleverly engineered mechanism those patches rely on, one would have to imitate that mechanism for the largest part, to be succesful. And it won't be easy to figure that out. I'm pretty certain that Fentanyl dissolved in ethanol won't work if dripped onto the skin. DMSO(DiMethylSulfOxide) might be a better alternative. DMSO has the unique property that it's an excellent solvent for many substances, and due to it's polarity can pass through the skin and maybe eveb into the mucles or a vein, where the substance dissolved in DMSO would reach the brain rather fast. The best place on the body to apply DMSO solution containing Fentanyl would be on one of the bulging veins at the junction of veins on the inside of the arm. Make shure, absolutely shure, that the dose isn't too high, or one could be a stiff in less than 5 minutes. Proper dosing of Fentanyl is serious business.

    For extracting the patch for sublingual use, I'll refer anyone who wants to read more about it, to my post in another thread.
     
  20. lazor

    lazor Newbie

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    One might try an extraction by letting the mylan patch soak in a small amount of isopropyl for a minimum of 24 hrs (preferably in a small clear glass container) After a good soaking, let the liquid evaporate off completely, you should find a residue of clearish crystals at bottom of glass. What you do from there is remove the residue using the best method avalible to you. Swim did this with a 50 mylan patch and was successful. It was just an experiment just to see if this was feasable. Swim would never do this for any other reason.