First hello everyone. My question is this. A friend of mine took 160 mg of amphetamine salts last night between 2 am and 6 am (half by mouth half by nose). He knows now he got carried away but he has been having two problems. The first is that when he is sitting his HR is about normal at 80 but when he stands it jumps to a quick 140 bpm. Also his fingers have been retaining fluid. He is tired and does think he could sleep but is scared and debating if he should go to the ER. A few more things. he is comfortable and never feels his heart pounding but only can tell by taking a pulse that the HR is raised. Also it is now 11 pm so about 21 hours after the entire thing began. Finally could he take diphenhydramine to help him sleep ( I hear it my raise HR or BP). Thanks a lot and sorry my first post is a long question oh and how much longer would you guys expect this to last.