New Amphetamine for Adhd Treatment!

Discussion in 'Amphetamine' started by sw2431, Mar 27, 2007.

  1. sw2431

    sw2431 Newbie

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    Lisdexamfetamine (L-lysine-d-amphetamine), marketed under the name Vyvanse, is a prodrug indicated for treatment of attention-deficit hyperactivity disorder. It was developed by Shire and New River Pharmaceuticals and received approval from the U.S. Food and Drug Administration on February 23, 2007. Lisdexamfetamine is intended to provide an option of lower abuse potential, and the results of clinical trials seem to indicate that it is successful. 50mg of lisdexamfetamine contains 20mg of the stimulant d-amphetamine, the well-known abusable Schedule II option; because of its being bound to L-Lysine, this amphetamine is released and activated more slowly as the molecule is hydrolyzed in the digestive system. This delayed release produced less "likeability", less euphoric effect and a later peak time than amphetamine alone in clinical trials, suggesting that lisdexamfetamine may be appropriate for use with patients with history of stimulant abuse. Nevertheless, it is currently up for designation as Schedule II as well.
     
  2. enquirewithin

    enquirewithin Gold Member

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    It seems to be just a time-release version of dexamphetamine.
     
  3. sw2431

    sw2431 Newbie

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  4. svenghali

    svenghali Silver Member

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    Time-release?! CRUSH IT!
     
  5. blinkKDX

    blinkKDX Newbie

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    looks like a new adderall with less fun factor
     
  6. SteeleyJ

    SteeleyJ Newbie

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    Crushing it won't work, it would still be bound to the L-Lysine making it slowly activated as the body hydrolyzes it. There must be a way to hydrolyze it into just d-amphetamine before it enters the body though. :crazy

    This whole thing looks to me to be thier next cash cow to push on the kids since their patent on Adderall XR is going to run out soon.
     
  7. jesusfreak666er

    jesusfreak666er Newbie

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    ugh gotta hate those drug companies attempts to ruin a good thing... call swim old fashioned but give him a 2 x 30mg tabs, 20 dollar bill, a credit card and hes flying...
     
  8. hoodabudda

    hoodabudda Silver Member

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    yeah dude you cant really top adderall unless they start putting shards in capsules.focalin/dexmeythlphenidate is the only thing that compares to amphetamine isho