I have been toying with an idea after doing some reading. The one particular phrase that caught his attention was "N2O seems to induce its effects through antagonism on NMDA receptors, GABA-A receptor potentiation and potassium channel activation, as well as having a benzodiazepine-like effect and stimulating endogenous opioid receptors." http://cat.inist.fr/?aModele=afficheN&cpsidt=3778179 is also another link that caught his attention. So he took 100 mg dxm to smooth out the playing field for the 300mg codeine taken shortly thereafter. - Did 7 cartridges of nitrous over the next hour and then spaced the rest out throughout the night. He was impressed with the outcome. The shift from nitrous space to opiate land was off the wall. The intensity was definetly amplified for the entire duration of the evening. I feel this is worth looking into a little deeper.